Results 1 - 50 of 113 results
, Elinder F, Madeja M, Zeberg H, Århem P., Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1. Biophys J. October 18, 2016; 111 (8): 1679-1691.
, Gupta K, Zamanian M, Bae C, Milescu M, Krepkiy D, Tilley DC, Sack JT, Yarov-Yarovoy V, Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels. Kim JI, Swartz KJ., Elife. July 9, 2015; 4 e06774.
, Sforna L, D'Adamo MC, Servettini I, Guglielmi L, Pessia M, Franciolini F, Catacuzzeno L., Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia. J Neurophysiol. April 1, 2015; 113 (7): 2653-65.
, Martin-Eauclaire MF, Ferracci G, Bosmans F, Bougis PE., A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif. J Gen Physiol. February 1, 2015; 145 (2): 155-62.
, Tang YQ, Zhou JH, Yang F, Zheng J, Wang K., The tetramerization domain potentiates Kv4 channel function by suppressing closed-state inactivation. Biophys J. September 2, 2014; 107 (5): 1090-1104.
, Tao H, Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels. Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP., Biochemistry. October 22, 2013; 52 (42): 7439-48.
, Heler R, Bell JK, Boland LM., Homology model and targeted mutagenesis identify critical residues for arachidonic acid inhibition of Kv4 channels. Channels (Austin). March 1, 2013; 7 (2): 74-84.
, Tao H, Wu Y, Deng M, He J, Wang M, Xiao Y, Liang S., Molecular determinants for the tarantula toxin jingzhaotoxin-I interacting with potassium channel Kv2.1. Toxicon. March 1, 2013; 63 129-36.
, Milescu M, Opening the shaker K+ channel with hanatoxin. Lee HC, Bae CH, Kim JI, Swartz KJ., J Gen Physiol. February 1, 2013; 141 (2): 203-16.
, Pless SA, Niciforovic AP, Galpin JD, Nunez JJ, Kurata HT, Ahern CA., A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel. Nat Commun. January 1, 2013; 4 1784.
, Smith KE, Wilkie SE, Tebbs-Warner JT, Jarvis BJ, Gallasch L, Stocker M, Hunt DM., Functional analysis of missense mutations in Kv8.2 causing cone dystrophy with supernormal rod electroretinogram. J Biol Chem. December 21, 2012; 287 (52): 43972-83.
, Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1. Gene. December 10, 2012; 511 (1): 26-33.
, Lacroix JJ, Pless SA, Maragliano L, Campos FV, Galpin JD, Ahern CA, Roux B, Bezanilla F., Intermediate state trapping of a voltage sensor. J Gen Physiol. December 1, 2012; 140 (6): 635-52.
, Yuan C, Liu Z, JZTX-XIII, a Kv channel gating modifier toxin from Chinese tarantula Chilobrachys jingzhao. Hu W, Gao T, Liang S., Toxicon. February 1, 2012; 59 (2): 265-71.
, Lin MC, Hsieh JY, Mock AF, Papazian DM., R1 in the Shaker S4 occupies the gating charge transfer center in the resting state. J Gen Physiol. August 1, 2011; 138 (2): 155-63.
, Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ., Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors. J Gen Physiol. July 1, 2011; 138 (1): 59-72.
, Madeja M, Steffen W, Mesic I, Garic B, Zhorov BS., Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1. J Biol Chem. October 29, 2010; 285 (44): 33898-905.
, Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels . Lee S, Milescu M, Jung HH, Lee JY, Bae CH, Lee CW, Kim HH, Swartz KJ, Kim JI., Biochemistry. June 29, 2010; 49 (25): 5134-42.
, Lin MC, Abramson J, Papazian DM., Transfer of ion binding site from ether-a- go-go to Shaker: Mg2+ binds to resting state to modulate channel opening. J Gen Physiol. May 1, 2010; 135 (5): 415-31.
, Lvov A, Greitzer D, Berlin S, Chikvashvili D, Tsuk S, Lotan I, Michaelevski I., Rearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gating. J Biol Chem. October 9, 2009; 284 (41): 28276-91.
, Martínez-François JR, Mutations reveal voltage gating of CNGA1 channels in saturating cGMP. Xu Y, Xu Y, Lu Z., J Gen Physiol. August 1, 2009; 134 (2): 151-64.
, Deng M, Kuang F, Sun Z, Tao H, Cai T, Zhong L, Chen Z, Xiao Y, Liang S., Jingzhaotoxin-IX, a novel gating modifier of both sodium and potassium channels from Chinese tarantula Chilobrachys jingzhao. Neuropharmacology. August 1, 2009; 57 (2): 77-87.
, Mazzolini M, Anselmi C, Torre V., The analysis of desensitizing CNGA1 channels reveals molecular interactions essential for normal gating. J Gen Physiol. April 1, 2009; 133 (4): 375-86.
, Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels. Lee SY, Banerjee A, MacKinnon R., PLoS Biol. March 3, 2009; 7 (3): e47.
, Barghaan J, Bähring R., Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels. J Gen Physiol. February 1, 2009; 133 (2): 205-24.
, Imbrici P, Grottesi A, D'Adamo MC, Mannucci R, Tucker SJ, Pessia M., Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties. Channels (Austin). January 1, 2009; 3 (1): 39-45.
, Bosmans F, Martin-Eauclaire MF, Swartz KJ., Deconstructing voltage sensor function and pharmacology in sodium channels. Nature. November 13, 2008; 456 (7219): 202-8.
, Gravagna NG, Knoeckel CS, Taylor AD, Hultgren BA, Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles. Ribera AB., J Comp Neurol. October 10, 2008; 510 (5): 508-24.
, Lvov A, Chikvashvili D, Michaelevski I, Lotan I., VAMP2 interacts directly with the N terminus of Kv2.1 to enhance channel inactivation. Pflugers Arch. September 1, 2008; 456 (6): 1121-36.
, Tsuk S, Lvov A, Michaelevski I, Chikvashvili D, Lotan I., Formation of the full SNARE complex eliminates interactions of its individual protein components with the Kv2.1 channel. Biochemistry. August 12, 2008; 47 (32): 8342-9.
, Lewis A, Jogini V, Blachowicz L, Lainé M, Roux B., Atomic constraints between the voltage sensor and the pore domain in a voltage-gated K+ channel of known structure. J Gen Physiol. June 1, 2008; 131 (6): 549-61.
, Ma Z, Wong KY, Horrigan FT., An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels. J Gen Physiol. May 1, 2008; 131 (5): 483-502.
, Milescu M, Vobecky J, Roh SH, Kim SH, Tarantula toxins interact with voltage sensors within lipid membranes. Jung HJ, Kim JI, Swartz KJ., J Gen Physiol. November 1, 2007; 130 (5): 497-511.
, Broomand A, Osterberg F, Wardi T, Elinder F., Electrostatic domino effect in the Shaker K channel turret. Biophys J. October 1, 2007; 93 (7): 2307-14.
, Czirjak G, Toth ZE, Enyedi P., Characterization of the heteromeric potassium channel formed by kv2.1 and the retinal subunit kv8.2 in Xenopus oocytes. J Neurophysiol. September 1, 2007; 98 (3): 1213-22.
, Liao Z, Yuan C, Peng K, Xiao Y, Liang S., Solution structure of Jingzhaotoxin-III, a peptide toxin inhibiting both Nav1.5 and Kv2.1 channels. Toxicon. July 1, 2007; 50 (1): 135-43.
, Yuan C, Yang S, Liao Z, Liang S., Effects and mechanism of Chinese tarantula toxins on the Kv2.1 potassium channels. Biochem Biophys Res Commun. January 19, 2007; 352 (3): 799-804.
, Liao Z, Yuan C, Deng M, Solution structure and functional characterization of jingzhaotoxin-XI: a novel gating modifier of both potassium and sodium channels. Li J, Chen J, Yang Y, Hu W, Liang S., Biochemistry. December 26, 2006; 45 (51): 15591-600.
, Wolf-Goldberg T, Michaelevski I, Sheu L, Gaisano HY, Chikvashvili D, Lotan I., Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels. Mol Pharmacol. September 1, 2006; 70 (3): 818-28.
, Gordon E, Cohen JL, Engel R, Abbott GW., 1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers. Mol Pharmacol. March 1, 2006; 69 (3): 718-26.
, Chapman ML, Blanke ML, Krovetz HS, VanDongen AM., Allosteric effects of external K+ ions mediated by the aspartate of the GYGD signature sequence in the Kv2.1 K+ channel. Pflugers Arch. March 1, 2006; 451 (6): 776-92.
, Gordon E, Roepke TK, Abbott GW., Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies. Biophys J. February 15, 2006; 90 (4): 1223-31.
, Hayama E, Imamura S, Analysis of voltage-gated potassium channel beta1 subunits in the porcine neonatal ductus arteriosus. Wu C, Nakazawa M, Matsuoka R, Nakanishi T., Pediatr Res. February 1, 2006; 59 (2): 167-74.
, Quinn CC, Begenisich T., Pharmacology and surface electrostatics of the K channel outer pore vestibule. J Membr Biol. January 1, 2006; 212 (1): 51-60.
, Chapman ML, VanDongen AM., K channel subconductance levels result from heteromeric pore conformations. J Gen Physiol. August 1, 2005; 126 (2): 87-103.
, Zarayskiy VV, Balasubramanian G, Bondarenko VE, Morales MJ., Heteropoda toxin 2 is a gating modifier toxin specific for voltage-gated K+ channels of the Kv4 family. Toxicon. March 15, 2005; 45 (4): 431-42.
, Tsuk S, Michaelevski I, Bentley GN, Joho RH, Chikvashvili D, Lotan I., Kv2.1 channel activation and inactivation is influenced by physical interactions of both syntaxin 1A and the syntaxin 1A/soluble N-ethylmaleimide-sensitive factor-25 (t-SNARE) complex with the C terminus of the channel. Mol Pharmacol. February 1, 2005; 67 (2): 480-8.
, Tammaro P, Smirnov SV, Moran O., Effects of intracellular magnesium on Kv1.5 and Kv2.1 potassium channels. Eur Biophys J. February 1, 2005; 34 (1): 42-51.
, Kitaguchi T, Sukhareva M, Swartz KJ., Stabilizing the closed S6 gate in the Shaker Kv channel through modification of a hydrophobic seal. J Gen Physiol. October 1, 2004; 124 (4): 319-32.
, Scholle A, Zimmer T, Koopmann R, Engeland B, Pongs O, Benndorf K., Effects of Kv1.2 intracellular regions on activation of Kv2.1 channels. Biophys J. August 1, 2004; 87 (2): 873-82.