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Summary Expression Phenotypes Gene Literature (46) GO Terms (0) Nucleotides (106) Proteins (36) Interactants (171) Wiki

Papers associated with ecdysoneless cell cycle regulator

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2 paper(s) referencing morpholinos

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Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs., Kumar A, Basak S, Rao S, Gicheru Y, Mayer ML, Sansom MSP, Chakrapani S., Nat Commun. January 1, 2020; 11 (1): 3752.            

Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs., Bernhard M, Laube B., Sci Rep. January 1, 2020; 10 (1): 16569.          

The desensitization pathway of GABAA receptors, one subunit at a time., Gielen M, Barilone N, Corringer PJ., Nat Commun. January 1, 2020; 11 (1): 5369.                

A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels., Wu Y, Chen Z, Canessa CM., Elife. January 1, 2019; 8               

ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development., Osório L, Wu X, Wang L, Jiang Z, Neideck C, Sheng G, Zhou Z., J Cell Biol. January 1, 2019; 218 (7): 2388-2402.                  

Gating control of the cardiac sodium channel Nav1.5 by its β3-subunit involves distinct roles for a transmembrane glutamic acid and the extracellular domain., Salvage SC, Zhu W, Habib ZF, Hwang SS, Irons JR, Huang CLH, Silva JR, Jackson AP., J Biol Chem. January 1, 2019; 294 (51): 19752-19763.            

Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models., Kryukova EV, Ivanov IA, Lebedev DS, Spirova EN, Egorova NS, Zouridakis M, Kasheverov IE, Tzartos SJ, Tsetlin VI., Mar Drugs. November 22, 2018; 16 (12):             

Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing., Henderson BJ, Grant S, Chu BW, Shahoei R, Huard SM, Saladi SSM, Tajkhorshid E, Dougherty DA, Lester HA., eNeuro. November 1, 2018; 5 (6):                   

EphA7 regulates claudin6 and pronephros development in Xenopus., Sun J, Wang X, Shi Y, Shi Y, Li J, Li C, Shi Z, Chen Y, Chen Y, Mao B., Biochem Biophys Res Commun. January 1, 2018; 495 (2): 1580-1587.        

Cryo-EM structure of 5-HT3A receptor in its resting conformation., Basak S, Gicheru Y, Samanta A, Molugu SK, Huang W, Fuente M, Hughes T, Taylor DJ, Nieman MT, Moiseenkova-Bell V, Chakrapani S., Nat Commun. January 1, 2018; 9 (1): 514.          

Identification of Novel Functionally Important Aromatic Residue Interactions in the Extracellular Domain of the Glycine Receptor., Tang B, Devenish SO, Lummis SCR., Biochemistry. January 1, 2018; 57 (27): 4029-4035.

Multiple regions in the extracellular domain of the glycine receptor determine receptor activity., Tang B, Lummis SCR., J Biol Chem. January 1, 2018; 293 (36): 13889-13896.                    

Structural basis of neurosteroid anesthetic action on GABAA receptors., Chen Q, Wells MM, Arjunan P, Tillman TS, Cohen AE, Xu Y, Xu Y, Tang P., Nat Commun. January 1, 2018; 9 (1): 3972.              

Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3A receptor., Basak S, Gicheru Y, Rao S, Sansom MSP, Chakrapani S., Nature. January 1, 2018; 563 (7730): 270-274.

A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation., Ghosh B, Tsao TW, Czajkowski C., Neuropharmacology. October 1, 2017; 125 343-352.

Digital dissection of the model organism Xenopus laevis using contrast-enhanced computed tomography., Porro LB, Richards CT., J Anat. August 1, 2017; 231 (2): 169-191.                        

Functional characterization of two prokaryotic pentameric ligand-gated ion channel chimeras - role of the GLIC transmembrane domain in proton sensing., Hénault CM, Baenziger JE., Biochim Biophys Acta Biomembr. February 1, 2017; 1859 (2): 218-227.

The Proton Responsiveness in the Extracellular Domain of GLIC Differs in the Presence of the ELIC Transmembrane Domain., Alqazzaz MA, Price KL, Lummis SCR., Biochemistry. January 1, 2017; 56 (15): 2134-2138.

Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors., Vulfius CA, Kasheverov IE, Kryukova EV, Spirova EN, Shelukhina IV, Starkov VG, Andreeva TV, Faure G, Zouridakis M, Tsetlin VI, Utkin YN., PLoS One. January 1, 2017; 12 (10): e0186206.            

Identification of a pre-active conformation of a pentameric channel receptor., Menny A, Lefebvre SN, Schmidpeter PA, Drège E, Fourati Z, Delarue M, Edelstein SJ, Nimigean CM, Joseph D, Corringer PJ., Elife. January 1, 2017; 6                             

Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors., Levitz J, Habrian C, Bharill S, Fu Z, Vafabakhsh R, Isacoff EY., Neuron. October 5, 2016; 92 (1): 143-159.                                  

Neurotoxic phospholipase A2 from rattlesnake as a new ligand and new regulator of prokaryotic receptor GLIC (proton-gated ion channel from G. violaceus)., Ostrowski M, Porowinska D, Prochnicki T, Prevost M, Raynal B, Baron B, Sauguet L, Corringer PJ, Faure G., Toxicon. June 15, 2016; 116 63-71.

The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening., Zheng F, Robertson AP, Abongwa M, Yu EW, Martin RJ., Int J Parasitol Drugs Drug Resist. April 1, 2016; 6 (1): 60-73.            

Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer., Kouvatsos N, Giastas P, Chroni-Tzartou D, Poulopoulou C, Tzartos SJ., Proc Natl Acad Sci U S A. January 1, 2016; 113 (34): 9635-40.

A chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation., Schmandt N, Velisetty P, Chalamalasetti SV, Stein RA, Bonner R, Talley L, Parker MD, Mchaourab HS, Yee VC, Lodowski DT, Chakrapani S., J Gen Physiol. October 1, 2015; 146 (4): 323-40.              

The NOTCH signaling pathway in normal and malignant blood cell production., Suresh S, Irvine AE., J Cell Commun Signal. March 1, 2015; 9 (1): 5-13.      

Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain., Zouridakis M, Giastas P, Zarkadas E, Chroni-Tzartou D, Bregestovski P, Tzartos SJ., Nat Struct Mol Biol. November 1, 2014; 21 (11): 976-80.

The comprehensive analysis of DEG/ENaC subunits in Hydra reveals a large variety of peptide-gated channels, potentially involved in neuromuscular transmission., Assmann M, Kuhn A, Dürrnagel S, Holstein TW, Gründer S., BMC Biol. October 3, 2014; 12 84.                      

Impact of intracellular domain flexibility upon properties of activated human 5-HT3 receptors., Kozuska JL, Paulsen IM, Belfield WJ, Martin IL, Cole DJ, Holt A, Dunn SM., Br J Pharmacol. April 1, 2014; 171 (7): 1617-28.      

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength., de Lau W, Peng WC, Gros P, Clevers H., Genes Dev. February 15, 2014; 28 (4): 305-16.          

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation., Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M., Proc Natl Acad Sci U S A. January 21, 2014; 111 (3): 966-71.        

The bile acid-sensitive ion channel (BASIC) is activated by alterations of its membrane environment., Schmidt A, Lenzig P, Oslender-Bujotzek A, Kusch J, Lucas SD, Gründer S, Wiemuth D., PLoS One. January 1, 2014; 9 (10): e111549.                    

Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators., Schramm A, Ebrahimi SN, Raith M, Zaugg J, Rueda DC, Hering S, Hamburger M., Phytochemistry. December 1, 2013; 96 318-29.

Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni., Dufour V, Beech RN, Wever C, Dent JA, Geary TG., PLoS Pathog. January 1, 2013; 9 (8): e1003586.            

Identification of GABA A receptor modulators in Kadsura longipedunculata and assignment of absolute configurations by quantum-chemical ECD calculations., Zaugg J, Ebrahimi SN, Smiesko M, Baburin I, Hering S, Hamburger M., Phytochemistry. December 1, 2011; 72 (18): 2385-95.

Engineering a prokaryotic Cys-loop receptor with a third functional domain., Goyal R, Salahudeen AA, Jansen M., J Biol Chem. October 7, 2011; 286 (40): 34635-42.

Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family., Duret G, Van Renterghem C, Weng Y, Prevost M, Moraga-Cid G, Huon C, Sonner JM, Corringer PJ., Proc Natl Acad Sci U S A. July 19, 2011; 108 (29): 12143-8.

Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis., Edelheit O, Hanukoglu I, Dascal N, Hanukoglu A., Am J Physiol Renal Physiol. April 1, 2011; 300 (4): F887-97.

The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development., Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR., Development. March 1, 2009; 136 (5): 729-38.            

DNA damage-induced replication arrest in Xenopus egg extracts., Stokes MP, Michael WM., J Cell Biol. October 27, 2003; 163 (2): 245-55.                

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos., Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR., Mol Cell. August 1, 2003; 12 (2): 425-35.                          

Immunocytochemical study of activin type IB receptor (XALK4) in Xenopus oocytes., Fukui A, Komazaki S, Miyoshi O, Asashima M., Dev Growth Differ. April 1, 2003; 45 (2): 113-9.        

Domains determining ligand specificity for Ca2+ receptors., Hammerland LG, Krapcho KJ, Garrett JE, Alasti N, Hung BC, Simin RT, Levinthal C, Nemeth EF, Fuller FH., Mol Pharmacol. April 1, 1999; 55 (4): 642-8.

Water-soluble nicotinic acetylcholine receptor formed by alpha7 subunit extracellular domains., Wells GB, Anand R, Wang F, Lindstrom J., J Biol Chem. January 9, 1998; 273 (2): 964-73.

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