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Summary Expression Phenotypes Gene Literature (117) GO Terms (4) Nucleotides (52) Proteins (37) Interactants (118) Wiki
XB--991583

Papers associated with kcna2



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Effects of the level of mRNA expression on biophysical properties, sensitivity to neurotoxins, and regulation of the brain delayed-rectifier K+ channels Kv1.2., Guillemare E, Honoré E, Pradier L, Lesage F, Schweitz H, Attali B, Barhanin J, Lazdunski M., Biochemistry. December 15, 1992; 31 (49): 12463-8.

Absence of effects of class III antiarrhythmic agents on cloned cardiac K channels., Yamagishi T, Ishii K, Taira N., Jpn J Pharmacol. April 1, 1993; 61 (4): 371-3.

Heteromultimeric assembly of human potassium channels. Molecular basis of a transient outward current?, Po S, Roberds S, Snyders DJ, Tamkun MM, Bennett PB., Circ Res. June 1, 1993; 72 (6): 1326-36.

Cloning and expression of a Kv1.2 class delayed rectifier K+ channel from canine colonic smooth muscle., Hart PJ, Overturf KE, Russell SN, Carl A, Hume JR, Sanders KM, Horowitz B., Proc Natl Acad Sci U S A. October 15, 1993; 90 (20): 9659-63.

Receptor-mediated modulation of rat KV1.2 in Xenopus oocytes., Murakoshi H, Ishii K, Nunoki K, Taira N., Eur J Pharmacol. August 16, 1994; 268 (3): 451-4.

Block by 4-aminopyridine of a Kv1.2 delayed rectifier K+ current expressed in Xenopus oocytes., Russell SN, Publicover NG, Hart PJ, Carl A, Hume JR, Sanders KM, Horowitz B., J Physiol. December 15, 1994; 481 ( Pt 3) 571-84.

Antiarrhythmic and bradycardic drugs inhibit currents of cloned K+ channels, KV1.2 and KV1.4., Yamagishi T, Ishii K, Taira N., Eur J Pharmacol. August 4, 1995; 281 (2): 151-9.

Slow inactivation conserved in heteromultimeric voltage-dependent K+ channels between Shaker (Kv1) and Shaw (Kv3) subfamilies., Shahidullah M, Hoshi N, Yokoyama S, Kawamura T, Higashida H., FEBS Lett. September 11, 1995; 371 (3): 307-10.

Microheterogeneity in heteromultimeric assemblies formed by Shaker (Kv1) and Shaw (Kv3) subfamilies of voltage-gated K+ channels., Shahidullah M, Hoshi N, Yokoyama S, Higashida H., Proc Biol Sci. September 22, 1995; 261 (1362): 309-17.

Suppression of two cloned smooth muscle-derived delayed rectifier potassium channels by cholinergic agonists and phorbol esters., Vogalis F, Ward M, Horowitz B., Mol Pharmacol. December 1, 1995; 48 (6): 1015-23.

Susceptibility of cloned K+ channels to reactive oxygen species., Duprat F, Guillemare E, Romey G, Fink M, Lesage F, Lazdunski M, Honore E., Proc Natl Acad Sci U S A. December 5, 1995; 92 (25): 11796-800.

Xenopus spinal neurons express Kv2 potassium channel transcripts during embryonic development., Burger C, Ribera AB., J Neurosci. February 15, 1996; 16 (4): 1412-21.          

Novel effects of dendrotoxin homologues on subtypes of mammalian Kv1 potassium channels expressed in Xenopus oocytes., Robertson B, Owen D, Stow J, Butler C, Newland C., FEBS Lett. March 25, 1996; 383 (1-2): 26-30.

Effects of charybdotoxin on K+ channel (KV1.2) deactivation and inactivation kinetics., Sprunger LK, Stewig NJ, O'Grady SM., Eur J Pharmacol. October 31, 1996; 314 (3): 357-64.

Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively., Tseng GN, Zhu B, Ling S, Yao JA., J Pharmacol Exp Ther. November 1, 1996; 279 (2): 844-55.

A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels. Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity., Cotton J, Crest M, Bouet F, Alessandri N, Gola M, Forest E, Karlsson E, Castañeda O, Harvey AL, Vita C, Ménez A., Eur J Biochem. February 15, 1997; 244 (1): 192-202.

The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes., Suessbrich H, Schönherr R, Heinemann SH, Attali B, Lang F, Busch AE., Br J Pharmacol. March 1, 1997; 120 (5): 968-74.

Maurotoxin, a four disulfide bridge toxin from Scorpio maurus venom: purification, structure and action on potassium channels., Kharrat R, Mansuelle P, Sampieri F, Crest M, Oughideni R, Van Rietschoten J, Martin-Eauclaire MF, Rochat H, El Ayeb M., FEBS Lett. April 14, 1997; 406 (3): 284-90.

Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241., Suessbrich H, Schönherr R, Heinemann SH, Lang F, Busch AE., FEBS Lett. September 8, 1997; 414 (2): 435-8.

Separable Kvbeta subunit domains alter expression and gating of potassium channels., Accili EA, Kiehn J, Yang Q, Wang Z, Brown AM, Wible BA., J Biol Chem. October 10, 1997; 272 (41): 25824-31.

Toxin and subunit specificity of blocking affinity of three peptide toxins for heteromultimeric, voltage-gated potassium channels expressed in Xenopus oocytes., Hopkins WF., J Pharmacol Exp Ther. June 1, 1998; 285 (3): 1051-60.

Receptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activity., Tsai W, Morielli AD, Cachero TG, Peralta EG., EMBO J. January 4, 1999; 18 (1): 109-18.

Differential sensitivity of voltage-gated potassium channels Kv1.5 and Kv1.2 to acidic pH and molecular identification of pH sensor., Steidl JV, Yool AJ., Mol Pharmacol. May 1, 1999; 55 (5): 812-20.

Distribution in rat brain of binding sites of kaliotoxin, a blocker of Kv1.1 and Kv1.3 alpha-subunits., Mourre C, Chernova MN, Martin-Eauclaire MF, Bessone R, Jacquet G, Gola M, Alper SL, Crest M., J Pharmacol Exp Ther. December 1, 1999; 291 (3): 943-52.

Mapping the functional anatomy of BgK on Kv1.1, Kv1.2, and Kv1.3. Clues to design analogs with enhanced selectivity., Alessandri-Haber N, Lecoq A, Gasparini S, Grangier-Macmath G, Jacquet G, Harvey AL, de Medeiros C, Rowan EG, Gola M, Ménez A, Crest M., J Biol Chem. December 10, 1999; 274 (50): 35653-61.

Regulation of Shaker-type potassium channels by hypoxia. Oxygen-sensitive K+ channels in PC12 cells., Conforti L, Millhorn DE., Adv Exp Med Biol. January 1, 2000; 475 265-74.

O2-sensitive K+ channels: role of the Kv1.2 -subunit in mediating the hypoxic response., Conforti L, Bodi I, Nisbet JW, Millhorn DE., J Physiol. May 1, 2000; 524 Pt 3 783-93.

Inhibition of the K+ channel kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation., Claydon TW, Boyett MR, Sivaprasadarao A, Ishii K, Owen JM, O'Beirne HA, Leach R, Komukai K, Orchard CH., J Physiol. July 15, 2000; 526 Pt 2 253-64.

Chemical synthesis and characterization of Pi1, a scorpion toxin from Pandinus imperator active on K+ channels., Fajloun Z, Carlier E, Lecomte C, Geib S, Di Luccio E, Bichet D, Mabrouk K, Rochat H, De Waard M, Sabatier JM., Eur J Biochem. August 1, 2000; 267 (16): 5149-55.

Gallamine triethiodide selectively blocks voltage-gated potassium channels in Ranvier nodes., Hinck D, Wulff H, Koppenhöfer E., Gen Physiol Biophys. March 1, 2001; 20 (1): 83-95.

Cloning and expression of three K+ channel cDNAs from Xenopus muscle., Fry M, Paterno G, Moody-Corbett F., Brain Res Mol Brain Res. June 20, 2001; 90 (2): 135-48.          

Expression and function of native potassium channel [K(V)alpha1] subunits in terminal arterioles of rabbit., Cheong A, Dedman AM, Beech DJ., J Physiol. August 1, 2001; 534 (Pt 3): 691-700.

Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2)., McCormack K, Connor JX, Zhou L, Ho LL, Ganetzky B, Chiu SY, Messing A., J Biol Chem. April 12, 2002; 277 (15): 13219-28.

Characteristics of brain Kv1 channels tailored to mimic native counterparts by tandem linkage of alpha subunits: implications for K+ channelopathies., Akhtar S, Shamotienko O, Papakosta M, Ali F, Dolly JO., J Biol Chem. May 10, 2002; 277 (19): 16376-82.

Modulation of voltage sensitivity by N-terminal cytoplasmic residues in human Kv1.2 channels., Varshney A, S K, Mathew MK., Eur Biophys J. September 1, 2002; 31 (5): 365-72.

Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin., Hattan D, Nesti E, Cachero TG, Morielli AD., J Biol Chem. October 11, 2002; 277 (41): 38596-606.

Local anesthetic block of Kv channels: role of the S6 helix and the S5-S6 linker for bupivacaine action., Nilsson J, Madeja M, Arhem P., Mol Pharmacol. June 1, 2003; 63 (6): 1417-29.

The pore region of the Kv1.2alpha subunit is an important component of recombinant Kv1.2 channel oxygen sensitivity., Conforti L, Takimoto K, Petrovic M, Pongs O, Millhorn D., Biochem Biophys Res Commun. June 27, 2003; 306 (2): 450-6.

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels., M'Barek S, Mosbah A, Sandoz G, Fajloun Z, Olamendi-Portugal T, Rochat H, Sampieri F, Guijarro JI, Mansuelle P, Delepierre M, De Waard M, Sabatier JM., Eur J Biochem. September 1, 2003; 270 (17): 3583-92.

Effects of Kv1.2 intracellular regions on activation of Kv2.1 channels., Scholle A, Zimmer T, Koopmann R, Engeland B, Pongs O, Benndorf K., Biophys J. August 1, 2004; 87 (2): 873-82.

Status of the intracellular gate in the activated-not-open state of shaker K+ channels., del Camino D, Kanevsky M, Yellen G., J Gen Physiol. November 1, 2005; 126 (5): 419-28.          

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS, Klement G, Almgren M, Sahlholm K, Nilsson J, Petersson S, Arhem P, Schalling M, Lavebratt C., BMC Neurosci. November 23, 2005; 6 65.          

Analysis of voltage-gated potassium channel beta1 subunits in the porcine neonatal ductus arteriosus., Hayama E, Imamura S, Wu C, Nakazawa M, Matsuoka R, Nakanishi T., Pediatr Res. February 1, 2006; 59 (2): 167-74.

Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate., Contreras JE, Holmgren M., J Gen Physiol. May 1, 2006; 127 (5): 481-94.                        

Membrane stretch slows the concerted step prior to opening in a Kv channel., Laitko U, Juranka PF, Morris CE., J Gen Physiol. June 1, 2006; 127 (6): 687-701.                  

The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae., Abdel-Mottaleb Y, Clynen E, Jalali A, Bosmans F, Vatanpour H, Schoofs L, Tytgat J., FEBS Lett. November 13, 2006; 580 (26): 6254-8.

Inhibition by bis(7)-tacrine of native delayed rectifier and KV1.2 encoded potassium channels., Nie H, Yu WJ, Li XY, Yuan CH, Pang YP, Li CY, Han YF, Li ZW., Neurosci Lett. January 29, 2007; 412 (2): 108-13.

The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes., Panaghie G, Abbott GW., J Gen Physiol. February 1, 2007; 129 (2): 121-33.                      

KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel., Nakajo K, Kubo Y., J Gen Physiol. September 1, 2007; 130 (3): 269-81.            

The role of distal S6 hydrophobic residues in the voltage-dependent gating of CaV2.3 channels., Raybaud A, Baspinar EE, Dionne F, Dodier Y, Sauvé R, Parent L., J Biol Chem. September 21, 2007; 282 (38): 27944-52.

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