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Summary Expression Phenotypes Gene Literature (141) GO Terms (0) Nucleotides (27) Proteins (24) Interactants (248) Wiki
XB-GENEPAGE-996922

Papers associated with abcc8



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Expression of Xenopus snail in mesoderm and prospective neural fold ectoderm., Essex LJ, Mayor R, Sargent MG., Dev Dyn. October 1, 1993; 198 (2): 108-22.              

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels., Ammälä C, Moorhouse A, Gribble F, Ashfield R, Proks P, Smith PA, Sakura H, Coles B, Ashcroft SJ, Ashcroft FM., Nature. February 8, 1996; 379 (6565): 545-8.

Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro., Sakura H, Wat N, Horton V, Millns H, Turner RC, Ashcroft FM., Diabetologia. October 1, 1996; 39 (10): 1233-6.

Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes., Gribble FM, Ashfield R, Ammälä C, Ashcroft FM., J Physiol. January 1, 1997; 498 ( Pt 1) 87-98.

The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide., Gribble FM, Tucker SJ, Ashcroft FM., EMBO J. March 17, 1997; 16 (6): 1145-52.

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor., Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM., Nature. May 8, 1997; 387 (6629): 179-83.

Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits., Trapp S, Tucker SJ, Ashcroft FM., Proc Natl Acad Sci U S A. August 5, 1997; 94 (16): 8872-7.

The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation., Gribble FM, Tucker SJ, Ashcroft FM., J Physiol. October 1, 1997; 504 ( Pt 1) 35-45.

Phentolamine block of KATP channels is mediated by Kir6.2., Proks P, Ashcroft FM., Proc Natl Acad Sci U S A. October 14, 1997; 94 (21): 11716-20.

Inhibition of the ATP-sensitive potassium channel from mouse pancreatic beta-cells by surfactants., Smith PA, Proks P., Br J Pharmacol. June 1, 1998; 124 (3): 529-39.

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit., Gribble FM, Tucker SJ, Haug T, Ashcroft FM., Proc Natl Acad Sci U S A. June 9, 1998; 95 (12): 7185-90.

Molecular determinants of KATP channel inhibition by ATP., Tucker SJ, Gribble FM, Proks P, Trapp S, Ryder TJ, Haug T, Reimann F, Ashcroft FM., EMBO J. June 15, 1998; 17 (12): 3290-6.

Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus., Mikhailov MV, Proks P, Ashcroft FM, Ashcroft SJ., FEBS Lett. June 16, 1998; 429 (3): 390-4.

Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine., Partiseti M, Collura V, Agnel M, Culouscou JM, Graham D., FEBS Lett. August 28, 1998; 434 (1-2): 171-6.

Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels., Gribble FM, Tucker SJ, Seino S, Ashcroft FM., Diabetes. September 1, 1998; 47 (9): 1412-8.

Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP., Trapp S, Proks P, Tucker SJ, Ashcroft FM., J Gen Physiol. September 1, 1998; 112 (3): 333-49.                

Mechanism of ATP-sensitive K channel inhibition by sulfhydryl modification., Trapp S, Tucker SJ, Ashcroft FM., J Gen Physiol. September 1, 1998; 112 (3): 325-32.          

Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA., Gribble FM, Proks P, Corkey BE, Ashcroft FM., J Biol Chem. October 9, 1998; 273 (41): 26383-7.

KATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit., Drain P, Li L, Wang J., Proc Natl Acad Sci U S A. November 10, 1998; 95 (23): 13953-8.

Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel., Bränström R, Leibiger IB, Leibiger B, Corkey BE, Berggren PO, Larsson O., J Biol Chem. November 20, 1998; 273 (47): 31395-400.

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP., Proks P, Gribble FM, Adhikari R, Tucker SJ, Ashcroft FM., J Physiol. January 1, 1999; 514 ( Pt 1) 19-25.

A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland., Otonkoski T, Ammälä C, Huopio H, Cote GJ, Chapman J, Cosgrove K, Ashfield R, Huang E, Komulainen J, Ashcroft FM, Dunne MJ, Kere J, Thomas PM., Diabetes. February 1, 1999; 48 (2): 408-15.

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP., Tanabe K, Tucker SJ, Matsuo M, Proks P, Ashcroft FM, Seino S, Amachi T, Ueda K., J Biol Chem. February 12, 1999; 274 (7): 3931-3.

The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na+ channel., Schreiber R, Hopf A, Mall M, Greger R, Kunzelmann K., Proc Natl Acad Sci U S A. April 27, 1999; 96 (9): 5310-5.

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel., Ashfield R, Gribble FM, Ashcroft SJ, Ashcroft FM., Diabetes. June 1, 1999; 48 (6): 1341-7.

Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide., Gribble FM, Ashcroft FM., Diabetologia. July 1, 1999; 42 (7): 845-8.

Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor., Reimann F, Tucker SJ, Proks P, Ashcroft FM., J Physiol. July 15, 1999; 518 ( Pt 2) 325-36.

A transmembrane domain of the sulfonylurea receptor mediates activation of ATP-sensitive K(+) channels by K(+) channel openers., D'hahan N, Jacquet H, Moreau C, Catty P, Vivaudou M., Mol Pharmacol. August 1, 1999; 56 (2): 308-15.

PKA-mediated phosphorylation of the human K(ATP) channel: separate roles of Kir6.2 and SUR1 subunit phosphorylation., Béguin P, Nagashima K, Nishimura M, Gonoi T, Seino S., EMBO J. September 1, 1999; 18 (17): 4722-32.

Interaction of vanadate with the cloned beta cell K(ATP) channel., Proks P, Ashfield R, Ashcroft FM., J Biol Chem. September 3, 1999; 274 (36): 25393-7.

Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A., Surah-Narwal S, Xu SZ, McHugh D, McDonald RL, Hough E, Cheong A, Partridge C, Sivaprasadarao A, Beech DJ., Br J Pharmacol. October 1, 1999; 128 (3): 667-72.

Effects of pond water, sediment, and sediment extracts from minnesota and vermont, USA, on early development and metamorphosis of xenopus., Fort DJ, Propst TL, Stover EL, Helgen JC, Levey RB, Gallagher K, Burkhart JG., Environ Toxicol Chem. October 1, 1999; 18 (10): 2305-2315.            

A novel sulfonylurea receptor family member expressed in the embryonic Drosophila dorsal vessel and tracheal system., Nasonkin I, Alikasifoglu A, Ambrose C, Cahill P, Cheng M, Sarniak A, Egan M, Thomas PM., J Biol Chem. October 8, 1999; 274 (41): 29420-5.

Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP., D'hahan N, Moreau C, Prost AL, Jacquet H, Alekseev AE, Terzic A, Vivaudou M., Proc Natl Acad Sci U S A. October 12, 1999; 96 (21): 12162-7.

The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP., Reimann F, Ryder TJ, Tucker SJ, Ashcroft FM., J Physiol. November 1, 1999; 520 Pt 3 661-9.

Altered functional properties of KATP channel conferred by a novel splice variant of SUR1., Sakura H, Trapp S, Liss B, Ashcroft FM., J Physiol. December 1, 1999; 521 Pt 2 337-50.

Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+ channel with an ABC transporter., Schwappach B, Zerangue N, Jan YN, Jan LY., Neuron. April 1, 2000; 26 (1): 155-67.

Rat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevis oocyte., Tanemoto M, Vanoye CG, Dong K, Welch R, Abe T, Hebert SC, Xu JZ., Am J Physiol Renal Physiol. April 1, 2000; 278 (4): F659-66.

Sensitivity of Kir6.2-SUR1 currents, in the absence and presence of sodium azide, to the K(ATP) channel inhibitors, ciclazindol and englitazone., McKay NG, Kinsella JM, Campbell CM, Ashford ML., Br J Pharmacol. June 1, 2000; 130 (4): 857-66.

Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A., Gribble FM, Reimann F, Ashfield R, Ashcroft FM., Mol Pharmacol. June 1, 2000; 57 (6): 1256-61.

Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide., Tanabe K, Tucker SJ, Ashcroft FM, Proks P, Kioka N, Amachi T, Ueda K., Biochem Biophys Res Commun. June 7, 2000; 272 (2): 316-9.

Identification of molecular regions responsible for the membrane trafficking of Kir6.2., Hough E, Beech DJ, Sivaprasadarao A., Pflugers Arch. July 1, 2000; 440 (3): 481-7.

Fast1 is required for the development of dorsal axial structures in zebrafish., Sirotkin HI, Gates MA, Kelly PD, Schier AF, Talbot WS., Curr Biol. September 7, 2000; 10 (17): 1051-4.

The antimalarial agent mefloquine inhibits ATP-sensitive K-channels., Gribble FM, Davis TM, Higham CE, Clark A, Ashcroft FM., Br J Pharmacol. October 1, 2000; 131 (4): 756-60.

Direct interaction of Na-azide with the KATP channel., Trapp S, Ashcroft FM., Br J Pharmacol. November 1, 2000; 131 (6): 1105-12.

Interaction of stilbene disulphonates with cloned K(ATP) channels., Proks P, Jones P, Ashcroft FM., Br J Pharmacol. March 1, 2001; 132 (5): 973-82.

ATP modulation of ATP-sensitive potassium channel ATP sensitivity varies with the type of SUR subunit., Song DK, Ashcroft FM., J Biol Chem. March 9, 2001; 276 (10): 7143-9.

Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel., Reimann F, Proks P, Ashcroft FM., Br J Pharmacol. April 1, 2001; 132 (7): 1542-8.

Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels., Song DK, Ashcroft FM., Br J Pharmacol. May 1, 2001; 133 (1): 193-9.

Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels., Dabrowski M, Wahl P, Holmes WE, Ashcroft FM., Diabetologia. June 1, 2001; 44 (6): 747-56.

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