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Summary Expression Phenotypes Gene Literature (63) GO Terms (3) Nucleotides (103) Proteins (41) Interactants (134) Wiki
XB-GENEPAGE-999159

Papers associated with slc3a1



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HNF1B Alters an Evolutionarily Conserved Nephrogenic Program of Target Genes., Grand K, Stoltz M, Rizzo L, Röck R, Kaminski MM, Salinas G, Getwan M, Naert T, Pichler R, Lienkamp SS., J Am Soc Nephrol. March 1, 2023; 34 (3): 412-432.                          


Modeling congenital kidney diseases in Xenopus laevis., Blackburn ATM, Miller RK., Dis Model Mech. April 9, 2019; 12 (4):       


Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging., Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Oriuchi N, Nagamori S, Kanai Y., Cancer Sci. March 1, 2016; 107 (3): 347-52.        


The molecular mechanism of intestinal levodopa absorption and its possible implications for the treatment of Parkinson's disease., Camargo SM, Vuille-dit-Bille RN, Mariotta L, Ramadan T, Huggel K, Singer D, Götze O, Verrey F., J Pharmacol Exp Ther. October 1, 2014; 351 (1): 114-23.


Heat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidney., Sauert K, Kahnert S, Roose M, Gull M, Brändli AW, Ryffel GU, Waldner C., PLoS One. January 1, 2012; 7 (3): e33522.                  


Characteristics of transport of selenoamino acids by epithelial amino acid transporters., Nickel A, Kottra G, Schmidt G, Danier J, Hofmann T, Daniel H., Chem Biol Interact. February 12, 2009; 177 (3): 234-41.


Organization of the pronephric kidney revealed by large-scale gene expression mapping., Raciti D, Reggiani L, Geffers L, Jiang Q, Bacchion F, Subrizi AE, Clements D, Tindal C, Davidson DR, Kaissling B, Brändli AW., Genome Biol. January 1, 2008; 9 (5): R84.                                                                        


Amino acid transport in schistosomes: Characterization of the permeaseheavy chain SPRM1hc., Krautz-Peterson G, Camargo S, Huggel K, Verrey F, Shoemaker CB, Skelly PJ., J Biol Chem. July 27, 2007; 282 (30): 21767-75.          


Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin., Malakauskas SM, Quan H, Fields TA, McCall SJ, Yu MJ, Kourany WM, Frey CW, Le TH., Am J Physiol Renal Physiol. February 1, 2007; 292 (2): F533-44.


The structural and functional units of heteromeric amino acid transporters. The heavy subunit rBAT dictates oligomerization of the heteromeric amino acid transporters., Fernández E, Jiménez-Vidal M, Calvo M, Zorzano A, Tebar F, Palacín M, Chillarón J., J Biol Chem. September 8, 2006; 281 (36): 26552-61.


Cystine and glutamate transport in renal epithelial cells transfected with human system x(-) (c)., Bridges CC, Zalups RK., Kidney Int. August 1, 2005; 68 (2): 653-64.


Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells., Su TZ, Feng MR, Weber ML., J Pharmacol Exp Ther. June 1, 2005; 313 (3): 1406-15.


Heterodimeric amino acid transporter glycoprotein domains determining functional subunit association., Franca R, Veljkovic E, Walter S, Wagner CA, Verrey F., Biochem J. June 1, 2005; 388 (Pt 2): 435-43.


The dopamine precursor L-dihydroxyphenylalanine is transported by the amino acid transporters rBAT and LAT2 in renal cortex., Quiñones H, Collazo R, Moe OW., Am J Physiol Renal Physiol. July 1, 2004; 287 (1): F74-80.


Functional characterization of Caenorhabditis elegans heteromeric amino acid transporters., Veljkovic E, Stasiuk S, Skelly PJ, Shoemaker CB, Verrey F., J Biol Chem. February 27, 2004; 279 (9): 7655-62.


Cystinuria-specific rBAT(R365W) mutation reveals two translocation pathways in the amino acid transporter rBAT-b0,+AT., Pineda M, Wagner CA, Bröer A, Stehberger PA, Kaltenbach S, Gelpí JL, Martín Del Río R, Zorzano A, Palacín M, Lang F, Bröer S., Biochem J. February 1, 2004; 377 (Pt 3): 665-74.


Expression of the activity of cystine/glutamate exchange transporter, system x(c)(-), by xCT and rBAT., Wang H, Tamba M, Kimata M, Sakamoto K, Bannai S, Sato H., Biochem Biophys Res Commun. June 6, 2003; 305 (3): 611-8.


Influence of rBAT-mediated amino acid transport on cytosolic pH., Moschèn I, Setiawan I, Palacin M, Bröer S, Albers A, Lang F., Nephron. August 1, 2002; 91 (4): 631-6.


Apical heterodimeric cystine and cationic amino acid transporter expressed in MDCK cells., Bauch C, Verrey F., Am J Physiol Renal Physiol. July 1, 2002; 283 (1): F181-9.


Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains., Matsuo H, Kanai Y, Kim JY, Chairoungdua A, Kim DK, Inatomi J, Shigeta Y, Ishimine H, Chaekuntode S, Tachampa K, Choi HW, Babu E, Fukuda J, Endou H., J Biol Chem. June 7, 2002; 277 (23): 21017-26.


Cystine transport activity of heterozygous rBAT mutants expressed in Xenopus oocytes., Ishihara M, Ogura T, Akakura K, Egoshi K, Mikami K, Nakaya H, Ito H., Nephron. June 1, 2002; 91 (2): 276-80.


Cloning and expression of the mouse glomerular podoplanin homologue gp38P., Boucherot A, Schreiber R, Pavenstädt H, Kunzelmann K., Nephrol Dial Transplant. June 1, 2002; 17 (6): 978-84.


Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain., Chairoungdua A, Kanai Y, Matsuo H, Inatomi J, Kim DK, Endou H., J Biol Chem. December 28, 2001; 276 (52): 49390-9.


Effects of gallium and mercury ions on transport systems., Moschèn, Schweizer K, Wagner CA, Geis-Gerstorfer J, Lang F., J Dent Res. August 1, 2001; 80 (8): 1753-7.


Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system xc-., Bassi MT, Gasol E, Manzoni M, Pineda M, Riboni M, Martín R, Zorzano A, Borsani G, Palacín M., Pflugers Arch. May 1, 2001; 442 (2): 286-96.


Human cystinuria-related transporter: localization and functional characterization., Mizoguchi K, Cha SH, Chairoungdua A, Kim DK, Shigeta Y, Matsuo H, Fukushima J, Awa Y, Akakura K, Goya T, Ito H, Endou H, Kanai Y., Kidney Int. May 1, 2001; 59 (5): 1821-33.


Cysteine residues in the C-terminus of the neutral- and basic-amino-acid transporter heavy-chain subunit contribute to functional properties of the system b(0,+)-type amino acid transporter., Peter GJ, Panova TB, Christie GR, Taylor PM., Biochem J. November 1, 2000; 351 Pt 3 677-82.


Involvement of rBAT in Na(+)-dependent and -independent transport of the neurotransmitter candidate L-DOPA in Xenopus laevis oocytes injected with rabbit small intestinal epithelium poly A(+) RNA., Ishiia H, Sasaki Y, Goshima Y, Kanai Y, Endou H, Ayusawa D, Ono H, Miyamae T, Misu Y., Biochim Biophys Acta. June 1, 2000; 1466 (1-2): 61-70.


Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids., Fukasawa Y, Segawa H, Kim JY, Chairoungdua A, Kim DK, Matsuo H, Cha SH, Endou H, Kanai Y., J Biol Chem. March 31, 2000; 275 (13): 9690-8.


The molecular basis of cystinuria: an update., Goodyer P, Boutros M, Rozen R., Exp Nephrol. January 1, 2000; 8 (3): 123-7.


LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine., Rossier G, Meier C, Bauch C, Summa V, Sordat B, Verrey F, Kühn LC., J Biol Chem. December 3, 1999; 274 (49): 34948-54.


Luminal heterodimeric amino acid transporter defective in cystinuria., Pfeiffer R, Loffing J, Rossier G, Bauch C, Meier C, Eggermann T, Loffing-Cueni D, Kühn LC, Verrey F., Mol Biol Cell. December 1, 1999; 10 (12): 4135-47.


Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria., Rajan DP, Kekuda R, Huang W, Wang H, Devoe LD, Leibach FH, Prasad PD, Ganapathy V., J Biol Chem. October 8, 1999; 274 (41): 29005-10.


Expression of membrane transporters in cane toad Bufo marinus oocytes., Markovich D, Regeer RR., J Exp Biol. August 1, 1999; 202 (Pt 16): 2217-23.


The mammalian homolog of the frog type II selenodeiodinase does not encode a functional enzyme in the rat., Leonard JL, Leonard DM, Safran M, Wu R, Zapp ML, Farwell AP., Endocrinology. May 1, 1999; 140 (5): 2206-15.


Progressive C-terminal deletions of the renal cystine transporter, NBAT, reveal a novel bimodal pattern of functional expression., Deora AB, Ghosh RN, Tate SS., J Biol Chem. December 4, 1998; 273 (49): 32980-7.


Cystinuria calls for heteromultimeric amino acid transporters., Palacín M, Estévez R, Zorzano A., Curr Opin Cell Biol. August 1, 1998; 10 (4): 455-61.


Discrimination of two amino acid transport activities in 4F2 heavy chain- expressing Xenopus laevis oocytes., Bröer A, Hamprecht B, Bröer S., Biochem J. August 1, 1998; 333 ( Pt 3) 549-54.


Molecular genetics of cystinuria: mutation analysis of SLC3A1 and evidence for another gene in type I (silent) phenotype., Saadi I, Chen XZ, Hediger M, Ong P, Pereira P, Goodyer P, Rozen R., Kidney Int. July 1, 1998; 54 (1): 48-55.


Transporters for cationic amino acids in animal cells: discovery, structure, and function., Devés R, Boyd CA., Physiol Rev. April 1, 1998; 78 (2): 487-545.


An intracellular trafficking defect in type I cystinuria rBAT mutants M467T and M467K., Chillarón J, Estévez R, Samarzija I, Waldegger S, Testar X, Lang F, Zorzano A, Busch A, Palacín M., J Biol Chem. April 4, 1997; 272 (14): 9543-9.


Recent advances in the biochemical and molecular biological basis of cystinuria., Gitomer WL, Pak CY., J Urol. December 1, 1996; 156 (6): 1907-12.


Obligatory amino acid exchange via systems bo,+-like and y+L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids., Chillarón J, Estévez R, Mora C, Wagner CA, Suessbrich H, Lang F, Gelpí JL, Testar X, Busch AE, Zorzano A, Palacín M., J Biol Chem. July 26, 1996; 271 (30): 17761-70.


The rBAT gene is responsible for L-cystine uptake via the b0,(+)-like amino acid transport system in a "renal proximal tubular" cell line (OK cells)., Mora C, Chillarón J, Calonge MJ, Forgo J, Testar X, Nunes V, Murer H, Zorzano A, Palacín M., J Biol Chem. May 3, 1996; 271 (18): 10569-76.


rBAT is an amino acid exchanger with variable stoichiometry., Coady MJ, Chen XZ, Lapointe JY., J Membr Biol. January 1, 1996; 149 (1): 1-8.


Molecular biology of mammalian amino acid transporters., Malandro MS, Kilberg MS., Annu Rev Biochem. January 1, 1996; 65 305-36.


Role of rBAT gene products in cystinuria., Miyamoto K, Katai K, Tatsumi S, Sone K, Segawa H, Takada K, Yamamoto H, Taketani Y, Morita K, Kanayama H, Kagawa S, Takeda E., Int J Urol. January 1, 1996; 3 (1 Suppl): S92-4.


Mutations of the basic amino acid transporter gene associated with cystinuria., Miyamoto K, Katai K, Tatsumi S, Sone K, Segawa H, Yamamoto H, Taketani Y, Takada K, Morita K, Kanayama H., Biochem J. September 15, 1995; 310 ( Pt 3) 951-5.


Heavy metal mediated inhibition of rBAT-induced amino acid transport., Waldegger S, Schmidt F, Herzer T, Gulbins E, Schuster A, Biber J, Markovich D, Murer H, Busch AE, Lang F., Kidney Int. June 1, 1995; 47 (6): 1677-81.


The nitroso-donor S-nitroso-cysteine regulates IsK expressed in Xenopus oocytes via a c-GMP independent mechanism., Raber G, Waldegger S, Herzer T, Gulbins E, Murer H, Busch AE, Lang F., Biochem Biophys Res Commun. February 6, 1995; 207 (1): 195-201.

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