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Summary Expression Gene Literature (24) GO Terms (20) Nucleotides (43) Proteins (24) Interactants (118) Wiki
XB--483408

Papers associated with pkd1

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1 paper(s) referencing morpholinos

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Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos., Naert T, Tulkens D, Edwards NA, Carron M, Shaidani NI, Wlizla M, Boel A, Demuynck S, Horb ME, Coucke P, Willaert A, Zorn AM, Vleminckx K, Vleminckx K., Sci Rep. January 1, 2020; 10 (1): 14662.                      


A PKD1L3 splice variant in taste buds is not cleaved at the G protein-coupled receptor proteolytic site., Kashyap P, Ng C, Wang Z, Li B, Arif Pavel M, Martin H, Yu Y., Biochem Biophys Res Commun. January 1, 2019; 512 (4): 812-818.


The ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex., Wang Z, Ng C, Liu X, Wang Y, Li B, Kashyap P, Chaudhry HA, Castro A, Kalontar EM, Ilyayev L, Walker R, Alexander RT, Qian F, Chen XZ, Yu Y., EMBO Rep. January 1, 2019; 20 (11): e48336.                            


Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney., Zhang B, Tran U, Wessely O., Development. January 1, 2018; 145 (6):                         


Characterization of potential TRPP2 regulating proteins in early Xenopus embryos., Futel M, Le Bouffant R, Buisson I, Umbhauer M, Riou JF., J Cell Biochem. January 1, 2018; 119 (12): 10338-10350.  


Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels., Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkley D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ., Nat Commun. January 1, 2018; 9 (1): 2302.            


Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2., Zheng W, Cai R, Hofmann L, Nesin V, Hu Q, Long W, Fatehi M, Liu X, Hussein S, Kong T, Li J, Light PE, Tang J, Flockerzi V, Tsiokas L, Chen XZ., Cell Rep. January 1, 2018; 22 (6): 1560-1573.          


The Sorting Nexin 3 Retromer Pathway Regulates the Cell Surface Localization and Activity of a Wnt-Activated Polycystin Channel Complex., Feng S, Streets AJ, Nesin V, Tran U, Nie H, Onopiuk M, Wessely O, Tsiokas L, Ong ACM., J Am Soc Nephrol. October 1, 2017; 28 (10): 2973-2984.


The polycystin complex mediates Wnt/Ca(2+) signalling., Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L., Nat Cell Biol. January 1, 2016; 18 (7): 752-764.              


Hereditary Renal Hypouricemia Type 1 and Autosomal Dominant Polycystic Kidney Disease., Stiburkova B, Stekrova J, Nakamura M, Ichida K., Am J Med Sci. October 1, 2015; 350 (4): 268-71.


A novel PKD2L1 C-terminal domain critical for trimerization and channel function., Zheng W, Hussein S, Yang J, Huang J, Zhang F, Hernandez-Anzaldo S, Fernandez-Patron C, Cao Y, Cao Y, Zeng H, Tang J, Chen XZ., Sci Rep. September 21, 2015; 5 9460.              


Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes., Iwase S, Sato R, De Bock PJ, Gevaert K, Fujiki S, Tawada T, Kuchitsu M, Yamagishi Y, Ono S, Abe H., Mol Biol Cell. June 1, 2013; 24 (12): 1933-46.            


Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation., Streets AJ, Wessely O, Peters DJ, Ong AC., Hum Mol Genet. May 15, 2013; 22 (10): 1924-39.


Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1., Woodward OM, Li Y, Yu S, Yu S, Greenwell P, Wodarczyk C, Boletta A, Guggino WB, Qian F., PLoS One. August 23, 2010; 5 (8): e12305.              


The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity., Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely O., Development. April 1, 2010; 137 (7): 1107-16.              


Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease., Li Y, Santoso NG, Yu S, Yu S, Woodward OM, Qian F, Guggino WB., J Biol Chem. December 25, 2009; 284 (52): 36431-41.


Structural and molecular basis of the assembly of the TRPP2/PKD1 complex., Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J., Proc Natl Acad Sci U S A. July 14, 2009; 106 (28): 11558-63.


Polycystic kidney disease and receptor for egg jelly is a plasma membrane protein of mouse sperm head., Butscheid Y, Chubanov V, Steger K, Meyer D, Dietrich A, Gudermann T., Mol Reprod Dev. March 1, 2006; 73 (3): 350-60.


Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling., Li Y, Wright JM, Qian F, Germino GG, Guggino WB., J Biol Chem. December 16, 2005; 280 (50): 41298-306.


Cloning and expression of the amphibian homologue of the human PKD1 gene., Burtey S, Leclerc C, Nabais E, Munch P, Gohory C, Moreau M, Fontés M., Gene. August 29, 2005; 357 (1): 29-36.          


Expression of the polycystin-1 C-terminal cytoplasmic tail increases Cl channel activity in Xenopus oocytes., Chernova MN, Vandorpe DH, Clark JS, Alper SL., Kidney Int. August 1, 2005; 68 (2): 632-41.


Cation channel regulation by COOH-terminal cytoplasmic tail of polycystin-1: mutational and functional analysis., Vandorpe DH, Wilhelm S, Jiang L, Ibraghimov-Beskrovnaya O, Chernova MN, Stuart-Tilley AK, Alper SL., Physiol Genomics. February 28, 2002; 8 (2): 87-98.


Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X., Chen XZ, Segal Y, Basora N, Guo L, Peng JB, Babakhanlou H, Vassilev PM, Brown EM, Hediger MA, Zhou J., Biochem Biophys Res Commun. April 20, 2001; 282 (5): 1251-6.


The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel., Vandorpe DH, Chernova MN, Jiang L, Sellin LK, Wilhelm S, Stuart-Tilley AK, Walz G, Alper SL., J Biol Chem. February 9, 2001; 276 (6): 4093-101.

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