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Summary Expression Phenotypes Gene Literature (43) GO Terms (20) Nucleotides (108) Proteins (51) Interactants (516) Wiki
XB--486780

Papers associated with axin1



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The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking., Azbazdar Y, De Robertis EM., Bioessays. January 1, 2024; 46 (1): e2300179.                            

RNF2 regulates Wnt/ß-catenin signaling via TCF7L1 destabilization., Koo Y, Han W, Keum BR, Lutz L, Yun SH, Kim GH, Han JK., Sci Rep. November 13, 2023; 13 (1): 19750.            

Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis., Azbazdar Y, Tejeda-Munoz N, Monka JC, Dayrit A, Binder G, Ozhan G, De Robertis EM., iScience. October 20, 2023; 26 (10): 108075.                

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E., Nat Commun. October 5, 2023; 14 (1): 6173.                                

Identification of protein phosphatase 4 catalytic subunit as a Wnt promoting factor in pan-cancer and Xenopus early embryogenesis., Wang Y, Han W, Yun S, Han J., Sci Rep. June 23, 2023; 13 (1): 10240.

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N, De Robertis EM., Proc Natl Acad Sci U S A. April 26, 2022; 119 (17): e2201008119.                          

A catenin of the plakophilin-subfamily, Pkp3, responds to canonical-Wnt pathway components and signals., Hong JY, Zapata J, Blackburn A, Baumert R, Bae SM, Ji H, Nam HJ, Miller RK, McCrea PD., Biochem Biophys Res Commun. July 23, 2021; 563 31-39.        

GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery., Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G, Schmid E, Piccolo S, Christofk HR, De Robertis EM., Cell Rep. July 28, 2020; 32 (4): 107973.                                      

PAWS1 controls Wnt signalling through association with casein kinase 1α., Bozatzi P, Dingwell KS, Wu KZ, Cooper F, Cummins TD, Hutchinson LD, Vogt J, Wood NT, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Smith JC, Sapkota GP., EMBO Rep. April 1, 2018; 19 (4):                             

Xenbase: a genomic, epigenomic and transcriptomic model organism database., Karimi K, Fortriede JD, Lotay VS, Burns KA, Wang DZ, Fisher ME, Fisher ME, Pells TJ, James-Zorn C, Wang Y, Ponferrada VG, Chu S, Chaturvedi P, Zorn AM, Vize PD., Nucleic Acids Res. January 4, 2018; 46 (D1): D861-D868.        

The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus., Zhu X, Xing R, Tan R, Dai R, Tao Q, Tao Q., Mech Dev. October 1, 2017; 147 28-36.              

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z, Lei A, Xu L, Chen L, Chen Y, Chen Y, Zhang X, Gao Y, Yang X, Zhang M, Cao Y, Cao Y., J Biol Chem. August 4, 2017; 292 (31): 12842-12859.        

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors., Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ., Sci Signal. June 27, 2017; 10 (485):


Apolipoprotein C-I mediates Wnt/Ctnnb1 signaling during neural border formation and is required for neural crest development., Yokota C, Åstrand C, Takahashi S, Hagey DW, Stenman JM., Int J Dev Biol. January 1, 2017; 61 (6-7): 415-425.                      

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ, Xie SX, Chen YT, Xue JL, Zhang CJ, Zhu F., World J Gastroenterol. September 7, 2016; 22 (33): 7486-99.      

Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin., Gillis WQ, Kirmizitas A, Iwasaki Y, Ki DH, Wyrick JM, Thomsen GH., Cell Commun Signal. August 2, 2016; 14 (1): 15.              

Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules., Nakamura Y, de Paiva Alves E, Veenstra GJ, Hoppler S., Development. June 1, 2016; 143 (11): 1914-25.            

Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways., Lee HJ, Shi DL, Zheng JJ., Elife. August 22, 2015; 4 e08142.                      

Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development., Sokol SY., Semin Cell Dev Biol. June 1, 2015; 42 78-85.      

In vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryos., Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S., J Cell Sci. September 15, 2014; 127 (Pt 18): 3970-82.                  

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.                            

Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling., Huang X, McGann JC, Liu BY, Hannoush RN, Lill JR, Pham V, Newton K, Kakunda M, Liu J, Yu C, Hymowitz SG, Hongo JA, Wynshaw-Boris A, Polakis P, Harland RM, Dixit VM., Science. March 22, 2013; 339 (6126): 1441-5.

Imparting regenerative capacity to limbs by progenitor cell transplantation., Lin G, Chen Y, Chen Y, Slack JM., Dev Cell. January 14, 2013; 24 (1): 41-51.                          

Single blastomere expression profiling of Xenopus laevis embryos of 8 to 32-cells reveals developmental asymmetry., Flachsova M, Sindelka R, Kubista M., Sci Rep. January 1, 2013; 3 2278.      

Differential role of Axin RGS domain function in Wnt signaling during anteroposterior patterning and maternal axis formation., Schneider PN, Slusarski DC, Houston DW., PLoS One. January 1, 2012; 7 (9): e44096.                

Cortical rotation and messenger RNA localization in Xenopus axis formation., Houston DW., Wiley Interdiscip Rev Dev Biol. January 1, 2012; 1 (3): 371-88.        

Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization., Kagermeier-Schenk B, Wehner D, Ozhan-Kizil G, Yamamoto H, Li J, Kirchner K, Hoffmann C, Stern P, Kikuchi A, Schambony A, Weidinger G., Dev Cell. December 13, 2011; 21 (6): 1129-43.        

Xenopus axin-related protein: a link between its centrosomal localization and function in the Wnt/beta-catenin pathway., Alexandrova EM, Sokol SY., Dev Dyn. January 1, 2010; 239 (1): 261-70.            

Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling., Goentoro L, Kirschner MW., Mol Cell. December 11, 2009; 36 (5): 872-84.                                      

Wnt/beta-catenin signaling: components, mechanisms, and diseases., MacDonald BT, Tamai K, He X., Dev Cell. July 1, 2009; 17 (1): 9-26.          

In vitro organogenesis from undifferentiated cells in Xenopus., Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T., Dev Dyn. June 1, 2009; 238 (6): 1309-20.                      

Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF., Matsui C, Kaieda S, Ikegami T, Mimori-Kiyosue Y., J Biol Chem. November 21, 2008; 283 (47): 33006-20.

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin., Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E, Lee E., Proc Natl Acad Sci U S A. June 10, 2008; 105 (23): 8032-7.        

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling., Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT., Science. May 18, 2007; 316 (5827): 1043-6.

Wnt/beta-catenin signaling regulates vertebrate limb regeneration., Kawakami Y, Rodriguez Esteban C, Raya M, Kawakami H, Martí M, Dubova I, Izpisúa Belmonte JC., Genes Dev. December 1, 2006; 20 (23): 3232-7.    

Identification and characterization of rat Dact1 and Dact2 genes in silico., Katoh M., Int J Mol Med. June 1, 2005; 15 (6): 1045-9.

PR72, a novel regulator of Wnt signaling required for Naked cuticle function., Creyghton MP, Roël G, Eichhorn PJ, Hijmans EM, Maurer I, Destrée O, Bernards R., Genes Dev. February 1, 2005; 19 (3): 376-86.            

Non-canonical Wnt signalling and regulation of gastrulation movements., Tada M, Concha ML, Heisenberg CP., Semin Cell Dev Biol. June 1, 2002; 13 (3): 251-60.

The HMG-box transcription factor XTcf-4 demarcates the forebrain-midbrain boundary., König A, Gradl D, Kühl M, Wedlich D., Mech Dev. May 1, 2000; 93 (1-2): 211-4.    

Relationship of vegetal cortical dorsal factors in the Xenopus egg with the Wnt/beta-catenin signaling pathway., Marikawa Y, Elinson RP., Mech Dev. December 1, 1999; 89 (1-2): 93-102.

Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function., Sakanaka C, Leong P, Xu L, Harrison SD, Williams LT., Proc Natl Acad Sci U S A. October 26, 1999; 96 (22): 12548-52.        

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation., Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X., Proc Natl Acad Sci U S A. May 25, 1999; 96 (11): 6273-8.            

Xenopus axin interacts with glycogen synthase kinase-3 beta and is expressed in the anterior midbrain., Hedgepeth CM, Deardorff MA, Klein PS., Mech Dev. February 1, 1999; 80 (2): 147-51.    

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