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Summary Expression Phenotypes Gene Literature (79) GO Terms (12) Nucleotides (67) Proteins (39) Interactants (179) Wiki
XB--494160

Papers associated with gja3



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Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation., Tovar LM, Burgos CF, Yévenes GE, Moraga-Cid G, Fuentealba J, Coddou C, Bascunan-Godoy L, Catrupay C, Torres A, Castro PA., Int J Mol Sci. January 21, 2023; 24 (3):                     

Molecular mechanisms underlying enhanced hemichannel function of a cataract-associated Cx50 mutant., Tong JJ, Khan U, Haddad BG, Minogue PJ, Beyer EC, Berthoud VM, Reichow SL, Ebihara L., Biophys J. December 21, 2021; 120 (24): 5644-5656.

4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation., Retamal MA, Fiori MC, Fernandez-Olivares A, Linsambarth S, Peña F, Quintana D, Stehberg J, Altenberg GA., Biochim Biophys Acta Mol Cell Biol Lipids. August 1, 2020; 1865 (8): 158705.

Cx46 hemichannel modulation by nitric oxide: Role of the fourth transmembrane helix cysteine and its possible involvement in cataract formation., Retamal MA, Orellana VP, Arévalo NJ, Rojas CG, Arjona RJ, Alcaíno CA, González W, Canan JG, Moraga-Amaro R, Stehberg J, Reuss L, Altenberg GA., Nitric Oxide. May 1, 2019; 86 54-62.

Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis., Piprek RP, Damulewicz M, Tassan JP, Kloc M, Kubiak JZ., Dev Genes Evol. May 1, 2019; 229 (2-3): 53-72.        

Concatenation of Human Connexin26 (hCx26) and Human Connexin46 (hCx46) for the Analysis of Heteromeric Gap Junction Hemichannels and Heterotypic Gap Junction Channels., Schadzek P, Hermes D, Stahl Y, Dilger N, Ngezahayo A., Int J Mol Sci. September 13, 2018; 19 (9):             

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels., Hu Z, Riquelme MA, Wang B, Bugay V, Brenner R, Gu S, Jiang JX., J Biol Chem. February 16, 2018; 293 (7): 2573-2585.

Calcium binding and voltage gating in Cx46 hemichannels., Pinto BI, Pupo A, García IE, Mena-Ulecia K, Martínez AD, Latorre R, Gonzalez C., Sci Rep. November 20, 2017; 7 (1): 15851.              

An optimized method for cryogenic storage of Xenopus sperm to maximise the effectiveness of research using genetically altered frogs., Pearl E, Morrow S, Noble A, Lerebours A, Horb M, Guille M., Theriogenology. April 1, 2017; 92 149-155.        

Charged Residues at the First Transmembrane Region Contribute to the Voltage Dependence of the Slow Gate of Connexins., Pinto BI, García IE, Pupo A, Retamal MA, Martínez AD, Latorre R, González C., J Biol Chem. July 22, 2016; 291 (30): 15740-52.

Carbon Monoxide Modulates Connexin Function through a Lipid Peroxidation-Dependent Process: A Hypothesis., Retamal MA., Front Physiol. June 28, 2016; 7 259.    

The cataract related mutation N188T in human connexin46 (hCx46) revealed a critical role for residue N188 in the docking process of gap junction channels., Schadzek P, Schlingmann B, Schaarschmidt F, Lindner J, Koval M, Heisterkamp A, Preller M, Ngezahayo A., Biochim Biophys Acta. January 1, 2016; 1858 (1): 57-66.                        

Differential regulation of Connexin50 and Connexin46 by PI3K signaling., Martinez JM, Wang HZ, Lin RZ, Brink PR, White TW., FEBS Lett. May 22, 2015; 589 (12): 1340-5.

The connexin46 mutant, Cx46T19M, causes loss of gap junction function and alters hemi-channel gating., Tong JJ, Minogue PJ, Kobeszko M, Beyer EC, Berthoud VM, Ebihara L., J Membr Biol. February 1, 2015; 248 (1): 145-55.                

Bisphenol A and 4-tert-Octylphenol Inhibit Cx46 Hemichannel Currents., Oh S., Korean J Physiol Pharmacol. January 1, 2015; 19 (1): 73-9.        

Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels., León-Paravic CG, Figueroa VA, Guzmán DJ, Valderrama CF, Vallejos AA, Fiori MC, Altenberg GA, Reuss L, Retamal MA., J Biol Chem. December 26, 2014; 289 (52): 36150-7.

Connexin 46 (cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleus., Slavi N, Rubinos C, Li L, Sellitto C, White TW, Mathias R, Srinivas M., J Biol Chem. November 21, 2014; 289 (47): 32694-702.

Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46., Tong JJ, Sohn BC, Lam A, Walters DE, Vertel BM, Ebihara L., Am J Physiol Cell Physiol. May 1, 2013; 304 (9): C823-32.

The food dye FD&C Blue No. 1 is a selective inhibitor of the ATP release channel Panx1., Wang J, Jackson DG, Dahl G., J Gen Physiol. May 1, 2013; 141 (5): 649-56.              

Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway., Figueroa V, Sáez PJ, Salas JD, Salas D, Jara O, Martínez AD, Sáez JC, Retamal MA., Biochim Biophys Acta. March 1, 2013; 1828 (3): 1169-79.

The role of the C-terminus in functional expression and internalization of rat connexin46 (rCx46)., Schlingmann B, Schadzek P, Hemmerling F, Schaarschmidt F, Heisterkamp A, Ngezahayo A., J Bioenerg Biomembr. February 1, 2013; 45 (1-2): 59-70.

Cataract-associated D3Y mutation of human connexin46 (hCx46) increases the dye coupling of gap junction channels and suppresses the voltage sensitivity of hemichannels., Schlingmann B, Schadzek P, Busko S, Heisterkamp A, Ngezahayo A., J Bioenerg Biomembr. October 1, 2012; 44 (5): 607-14.

The N-terminal half of the connexin protein contains the core elements of the pore and voltage gates., Kronengold J, Srinivas M, Verselis VK., J Membr Biol. August 1, 2012; 245 (8): 453-63.

Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium., Rubinos C, Sánchez HA, Verselis VK, Srinivas M., J Gen Physiol. January 1, 2012; 139 (1): 69-82.                    

Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2., Xia CH, Chang B, Derosa AM, Cheng C, White TW, Gong X., PLoS One. January 1, 2012; 7 (12): e52894.          

Biphasic effect of linoleic acid on connexin 46 hemichannels., Retamal MA, Evangelista-Martínez F, León-Paravic CG, Altenberg GA, Reuss L., Pflugers Arch. June 1, 2011; 461 (6): 635-43.

Properties of connexin 46 hemichannels in dissociated lens fiber cells., Ebihara L, Tong JJ, Vertel B, White TW, Chen TL., Invest Ophthalmol Vis Sci. February 1, 2011; 52 (2): 882-9.

Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other., Ambrosi C, Gassmann O, Pranskevich JN, Boassa D, Smock A, Wang J, Dahl G, Steinem C, Sosinsky GE., J Biol Chem. August 6, 2010; 285 (32): 24420-31.                    

Functional analysis of hemichannels and gap-junctional channels formed by connexins 43 and 46., Hoang QV, Qian H, Ripps H., Mol Vis. July 15, 2010; 16 1343-52.              

Voltage-dependent facilitation of Cx46 hemichannels., Retamal MA, Yin S, Altenberg GA, Reuss L., Am J Physiol Cell Physiol. January 1, 2010; 298 (1): C132-9.

Modulation of Cx46 hemichannels by nitric oxide., Retamal MA, Yin S, Altenberg GA, Reuss L., Am J Physiol Cell Physiol. June 1, 2009; 296 (6): C1356-63.

Conformational changes in a pore-forming region underlie voltage-dependent "loop gating" of an unapposed connexin hemichannel., Tang Q, Dowd TL, Verselis VK, Bargiello TA., J Gen Physiol. June 1, 2009; 133 (6): 555-70.                    

Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis., Shakespeare TI, Sellitto C, Li L, Rubinos C, Gong X, Srinivas M, White TW., Mol Biol Cell. May 1, 2009; 20 (10): 2582-92.

Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner., Banks EA, Toloue MM, Shi Q, Zhou ZJ, Liu J, Nicholson BJ, Jiang JX., J Cell Sci. February 1, 2009; 122 (Pt 3): 378-88.

Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating., Verselis VK, Srinivas M., J Gen Physiol. September 1, 2008; 132 (3): 315-27.            

Phosphorylation in the C-terminus of the rat connexin46 (rCx46) and regulation of the conducting activity of the formed connexons., Walter WJ, Zeilinger C, Bintig W, Kolb HA, Ngezahayo A., J Bioenerg Biomembr. August 1, 2008; 40 (4): 397-405.

A novel connexin50 mutation associated with congenital nuclear pulverulent cataracts., Arora A, Minogue PJ, Liu X, Addison PK, Russel-Eggitt I, Webster AR, Hunt DM, Ebihara L, Beyer EC, Berthoud VM, Moore AT., J Med Genet. March 1, 2008; 45 (3): 155-60.

Transgenic overexpression of connexin50 induces cataracts., Chung J, Berthoud VM, Novak L, Zoltoski R, Heilbrunn B, Minogue PJ, Liu X, Ebihara L, Kuszak J, Beyer EC., Exp Eye Res. March 1, 2007; 84 (3): 513-28.

Knock-in of alpha3 connexin prevents severe cataracts caused by an alpha8 point mutation., Xia CH, Cheung D, DeRosa AM, Chang B, Lo WK, White TW, Gong X., J Cell Sci. May 15, 2006; 119 (Pt 10): 2138-44.

Regulation of connexin hemichannels by monovalent cations., Srinivas M, Calderon DP, Kronengold J, Verselis VK., J Gen Physiol. January 1, 2006; 127 (1): 67-75.          

Cosegregation of permeability and single-channel conductance in chimeric connexins., Ma M, Dahl G., Biophys J. January 1, 2006; 90 (1): 151-63.

An aberrant sequence in a connexin46 mutant underlies congenital cataracts., Minogue PJ, Liu X, Ebihara L, Beyer EC, Berthoud VM., J Biol Chem. December 9, 2005; 280 (49): 40788-95.

Xenopus connexins: how frogs bridge the gap., de Boer TP, van der Heyden MA., Differentiation. September 1, 2005; 73 (7): 330-40.

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes., Bruzzone R, Barbe MT, Jakob NJ, Monyer H., J Neurochem. March 1, 2005; 92 (5): 1033-43.

Correlative studies of gating in Cx46 and Cx50 hemichannels and gap junction channels., Srinivas M, Kronengold J, Bukauskas FF, Bargiello TA, Verselis VK., Biophys J. March 1, 2005; 88 (3): 1725-39.

Connexins are mechanosensitive., Bao L, Sachs F, Dahl G., Am J Physiol Cell Physiol. November 1, 2004; 287 (5): C1389-95.

Exchange of gating properties between rat cx46 and chicken cx45.6., Tong JJ, Liu X, Dong L, Ebihara L., Biophys J. October 1, 2004; 87 (4): 2397-406.

Connexin 48.5 is required for normal cardiovascular function and lens development in zebrafish embryos., Cheng S, Shakespeare T, Mui R, White TW, Valdimarsson G., J Biol Chem. August 27, 2004; 279 (35): 36993-7003.

Accessibility of cx46 hemichannels for uncharged molecules and its modulation by voltage., Qu Y, Dahl G., Biophys J. March 1, 2004; 86 (3): 1502-9.

Opening hemichannels in nonjunctional membrane stimulates gap junction formation., Beahm DL, Hall JE., Biophys J. February 1, 2004; 86 (2): 781-96.

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