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Summary Expression Phenotypes Gene Literature (7) GO Terms (1) Nucleotides (148) Proteins (51) Interactants (23) Wiki
XB--5805213

Papers associated with prtn3



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Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability., Fu Z, Thorpe M, Akula S, Chahal G, Hellman LT., Front Immunol. September 12, 2018; 9 2387.                      

Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain., Zhao P, Lieu T, Barlow N, Sostegni S, Haerteis S, Korbmacher C, Liedtke W, Jimenez-Vargas NN, Vanner SJ, Bunnett NW., J Biol Chem. May 29, 2015; 290 (22): 13875-87.

Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase., Sostegni S, Diakov A, McIntyre P, Bunnett N, Korbmacher C, Haerteis S., Pflugers Arch. April 1, 2015; 467 (4): 687-701.

Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S., Haerteis S, Krappitz M, Bertog M, Krappitz A, Baraznenok V, Henderson I, Lindström E, Murphy JE, Bunnett NW, Korbmacher C., Pflugers Arch. October 1, 2012; 464 (4): 353-65.                  

Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel., Haerteis S, Krappitz M, Diakov A, Krappitz A, Rauh R, Korbmacher C., J Gen Physiol. October 1, 2012; 140 (4): 375-89.                      

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels., Diakov A, Bera K, Mokrushina M, Krueger B, Korbmacher C., J Physiol. October 1, 2008; 586 (19): 4587-608.

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes., Harris M, Firsov D, Vuagniaux G, Stutts MJ, Rossier BC., J Biol Chem. January 5, 2007; 282 (1): 58-64.

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