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Summary Expression Phenotypes Gene Literature (39) GO Terms (9) Nucleotides (85) Proteins (57) Interactants (40) Wiki
XB--5943216

Papers associated with slco1b3



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In vitro and physiologically-based pharmacokinetic based assessment of drug-drug interaction potential of canagliflozin., Mamidi RNVS, Dallas S, Sensenhauser C, Lim HK, Scheers E, Verboven P, Cuyckens F, Leclercq L, Evans DC, Kelley MF, Johnson MD, Snoeys J., Br J Clin Pharmacol. May 1, 2017; 83 (5): 1082-1096.

Characterization of 22 Antituberculosis Drugs for Inhibitory Interaction Potential on Organic Anionic Transporter Polypeptide (OATP)-Mediated Uptake., Parvez MM, Jung JA, Shin HJ, Kim DH, Shin JG., Antimicrob Agents Chemother. April 22, 2016; 60 (5): 3096-105.

Organic anion transporting polypeptide-mediated transport of, and inhibition by, asunaprevir, an inhibitor of hepatitis C virus NS3 protease., Eley T, Han YH, Huang SP, He B, Li W, Bedford W, Stonier M, Gardiner D, Sims K, Rodrigues AD, Bertz RJ., Clin Pharmacol Ther. February 1, 2015; 97 (2): 159-66.

Influence of drug formulation on OATP1B-mediated transport of paclitaxel., Nieuweboer AJ, Hu S, Gui C, Hagenbuch B, Ghobadi Moghaddam-Helmantel IM, Gibson AA, de Bruijn P, Mathijssen RH, Sparreboom A., Cancer Res. June 1, 2014; 74 (11): 3137-45.

Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition., Mikkaichi T, Yoshigae Y, Masumoto H, Imaoka T, Rozehnal V, Fischer T, Okudaira N, Izumi T., Drug Metab Dispos. April 1, 2014; 42 (4): 520-8.

Transport characteristics and transporter-based drug-drug interactions of TM-25659, a novel TAZ modulator., Choi MK, Kwon M, Ahn JH, Kim NJ, Bae MA, Song IS., Biopharm Drug Dispos. April 1, 2014; 35 (3): 183-94.

Rilpivirine inhibits drug transporters ABCB1, SLC22A1, and SLC22A2 in vitro., Moss DM, Liptrott NJ, Curley P, Siccardi M, Back DJ, Owen A., Antimicrob Agents Chemother. November 1, 2013; 57 (11): 5612-8.

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport., Svoboda M, Wlcek K, Taferner B, Hering S, Stieger B, Tong D, Zeillinger R, Thalhammer T, Jäger W., Biomed Pharmacother. September 1, 2011; 65 (6): 417-26.

Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green., de Graaf W, Häusler S, Heger M, van Ginhoven TM, van Cappellen G, Bennink RJ, Kullak-Ublick GA, Hesselmann R, van Gulik TM, Stieger B., J Hepatol. April 1, 2011; 54 (4): 738-45.

Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters., Walker AL, Franke RM, Sparreboom A, Ware RE., Exp Hematol. April 1, 2011; 39 (4): 446-56.

Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3., Martinez-Becerra P, Briz O, Romero MR, Macias RI, Perez MJ, Sancho-Mateo C, Lostao MP, Fernandez-Abalos JM, Marin JJ., Mol Pharmacol. March 1, 2011; 79 (3): 596-607.

Raltegravir is a substrate for SLC22A6: a putative mechanism for the interaction between raltegravir and tenofovir., Moss DM, Kwan WS, Liptrott NJ, Smith DL, Siccardi M, Khoo SH, Back DJ, Owen A., Antimicrob Agents Chemother. February 1, 2011; 55 (2): 879-87.

Characterization of digoxin uptake in sandwich-cultured human hepatocytes., Kimoto E, Chupka J, Xiao Y, Bi YA, Duignan DB., Drug Metab Dispos. January 1, 2011; 39 (1): 47-53.

Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer., Maeda T, Irokawa M, Arakawa H, Kuraoka E, Nozawa T, Tateoka R, Itoh Y, Nakanishi T, Tamai I., J Steroid Biochem Mol Biol. October 1, 2010; 122 (4): 180-5.

Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis., Connors KA, Korte JJ, Anderson GW, Degitz SJ., Gen Comp Endocrinol. August 1, 2010; 168 (1): 149-59.            

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms., Hartkoorn RC, Kwan WS, Shallcross V, Chaikan A, Liptrott N, Egan D, Sora ES, James CE, Gibbons S, Bray PG, Back DJ, Khoo SH, Owen A., Pharmacogenet Genomics. February 1, 2010; 20 (2): 112-20.

Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters., Hu S, Chen Z, Franke R, Orwick S, Zhao M, Rudek MA, Sparreboom A, Baker SD., Clin Cancer Res. October 1, 2009; 15 (19): 6062-9.

Pharmacogenetic pathway analysis of docetaxel elimination., Baker SD, Verweij J, Cusatis GA, van Schaik RH, Marsh S, Orwick SJ, Franke RM, Hu S, Schuetz EG, Lamba V, Messersmith WA, Wolff AC, Carducci MA, Sparreboom A., Clin Pharmacol Ther. February 1, 2009; 85 (2): 155-63.

Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies., Ghibellini G, Leslie EM, Pollack GM, Brouwer KL., Pharm Res. August 1, 2008; 25 (8): 1851-60.

Interaction of imatinib with human organic ion carriers., Hu S, Franke RM, Filipski KK, Hu C, Orwick SJ, de Bruijn EA, Burger H, Baker SD, Sparreboom A., Clin Cancer Res. May 15, 2008; 14 (10): 3141-8.

Identification and species similarity of OATP transporters responsible for hepatic uptake of beta-lactam antibiotics., Nakakariya M, Shimada T, Irokawa M, Maeda T, Tamai I., Drug Metab Pharmacokinet. January 1, 2008; 23 (5): 347-55.

Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport., Mahagita C, Grassl SM, Piyachaturawat P, Ballatori N., Am J Physiol Gastrointest Liver Physiol. July 1, 2007; 293 (1): G271-8.

The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver., Meier-Abt F, Hammann-Hänni A, Stieger B, Ballatori N, Boyer JL., Toxicol Appl Pharmacol. February 1, 2007; 218 (3): 274-9.

Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics., Smith NF, Marsh S, Scott-Horton TJ, Hamada A, Mielke S, Mross K, Figg WD, Verweij J, McLeod HL, Sparreboom A., Clin Pharmacol Ther. January 1, 2007; 81 (1): 76-82.

Characterization of hepatobiliary transport systems of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035., Tsuda-Tsukimoto M, Maeda T, Iwanaga T, Kume T, Tamai I., Pharm Res. November 1, 2006; 23 (11): 2646-56.

OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?, Briz O, Romero MR, Martinez-Becerra P, Macias RI, Perez MJ, Jimenez F, San Martin FG, Marin JJ., J Biol Chem. October 13, 2006; 281 (41): 30326-35.

Factors affecting the pharmacokinetic profile of MS-275, a novel histone deacetylase inhibitor, in patients with cancer., Acharya MR, Karp JE, Sausville EA, Hwang K, Ryan Q, Gojo I, Venitz J, Figg WD, Sparreboom A., Invest New Drugs. September 1, 2006; 24 (5): 367-75.

OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker., Nakagomi-Hagihara R, Nakai D, Kawai K, Yoshigae Y, Tokui T, Abe T, Ikeda T., Drug Metab Dispos. May 1, 2006; 34 (5): 862-9.

Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase., Fujino H, Saito T, Ogawa S, Kojima J., J Pharm Pharmacol. October 1, 2005; 57 (10): 1305-11.

Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel., Smith NF, Acharya MR, Desai N, Figg WD, Sparreboom A., Cancer Biol Ther. August 1, 2005; 4 (8): 815-8.

Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin., Fischer WJ, Altheimer S, Cattori V, Meier PJ, Dietrich DR, Hagenbuch B., Toxicol Appl Pharmacol. March 15, 2005; 203 (3): 257-63.

Identification of phalloidin uptake systems of rat and human liver., Meier-Abt F, Faulstich H, Hagenbuch B., Biochim Biophys Acta. July 1, 2004; 1664 (1): 64-9.

Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity., Nozawa T, Sugiura S, Nakajima M, Goto A, Yokoi T, Nezu J, Tsuji A, Tamai I., Drug Metab Dispos. March 1, 2004; 32 (3): 291-4.

Interactions of glycyrrhizin with organic anion transporting polypeptides of rat and human liver., Ismair MG, Stanca C, Ha HR, Renner EL, Meier PJ, Kullak-Ublick GA., Hepatol Res. August 1, 2003; 26 (4): 343-347.

Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin., Briz O, Serrano MA, MacIas RI, Gonzalez-Gallego J, Marin JJ., Biochem J. May 1, 2003; 371 (Pt 3): 897-905.

Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter., Pizzagalli F, Hagenbuch B, Stieger B, Klenk U, Folkers G, Meier PJ., Mol Endocrinol. October 1, 2002; 16 (10): 2283-96.

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver., Vavricka SR, Van Montfoort J, Ha HR, Meier PJ, Fattinger K., Hepatology. July 1, 2002; 36 (1): 164-72.

Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver., Ismair MG, Stieger B, Cattori V, Hagenbuch B, Fried M, Meier PJ, Kullak-Ublick GA., Gastroenterology. November 1, 2001; 121 (5): 1185-90.

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver., Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, Hagenbuch B., Gastroenterology. February 1, 2001; 120 (2): 525-33.

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