Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (109) GO Terms (5) Nucleotides (94) Proteins (45) Interactants (174) Wiki
XB--876601

Papers associated with gja1



???displayGene.coCitedPapers???

???pagination.result.count???

???pagination.result.page??? 1 2 3 ???pagination.result.next???

Sort Newest To Oldest Sort Oldest To Newest

Increased Hemichannel Activity Displayed by a Connexin43 Mutation Causing a Familial Connexinopathy Exhibiting Hypotrichosis with Follicular Keratosis and Hyperostosis., Crouthamel OE, Li L, Dilluvio MT, White TW., Int J Mol Sci. January 22, 2023; 24 (3):           

Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation., Tovar LM, Burgos CF, Yévenes GE, Moraga-Cid G, Fuentealba J, Coddou C, Bascunan-Godoy L, Catrupay C, Torres A, Castro PA., Int J Mol Sci. January 21, 2023; 24 (3):                     

GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base., Jang DG, Kwon KY, Kweon YC, Kim BG, Myung K, Lee HS, Young Park C, Kwon T, Park TJ., Elife. August 25, 2022; 11                                       

Cellular responses in the FGF10-mediated improvement of hindlimb regenerative capacity in Xenopus laevis revealed by single-cell transcriptomics., Yanagi N, Kato S, Fukazawa T, Kubo T., Dev Growth Differ. August 1, 2022; 64 (6): 266-278.      

Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M., Cell. April 15, 2021;               

S-nitrosylation of connexin43 hemichannels elicits cardiac stress-induced arrhythmias in Duchenne muscular dystrophy mice., Lillo MA, Himelman E, Shirokova N, Xie LH, Fraidenraich D, Contreras JE., JCI Insight. December 19, 2019; 4 (24):                                 

Structural determinants underlying permeant discrimination of the Cx43 hemichannel., Nielsen BS, Zonta F, Farkas T, Litman T, Nielsen MS, MacAulay N., J Biol Chem. November 8, 2019; 294 (45): 16789-16803.              

Connexin43 mutations linked to skin disease have augmented hemichannel activity., Srinivas M, Jannace TF, Cocozzelli AG, Li L, Slavi N, Sellitto C, White TW., Sci Rep. January 10, 2019; 9 (1): 19.              

Directional coupling of oligodendrocyte connexin-47 and astrocyte connexin-43 gap junctions., Fasciani I, Pluta P, González-Nieto D, Martínez-Montero P, Molano J, Paíno CL, Millet O, Barrio LC., Glia. November 1, 2018; 66 (11): 2340-2352.

Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo., Kotini M, Barriga EH, Leslie J, Gentzel M, Rauschenberger V, Schambony A, Mayor R., Nat Commun. September 21, 2018; 9 (1): 3846.                    

Cellular composition and organization of the spinal cord central canal during metamorphosis of the frog Xenopus laevis., Edwards-Faret G, Cebrián-Silla A, Méndez-Olivos EE, González-Pinto K, García-Verdugo JM, Larraín J., J Comp Neurol. July 1, 2018; 526 (10): 1712-1732.

Two Different Functions of Connexin43 Confer Two Different Bone Phenotypes in Zebrafish., Misu A, Yamanaka H, Aramaki T, Kondo S, Skerrett IM, Iovine MK, Watanabe M., J Biol Chem. June 10, 2016; 291 (24): 12601-11.

Isoform-specific phosphorylation-dependent regulation of connexin hemichannels., Alstrøm JS, Hansen DB, Nielsen MS, MacAulay N., J Neurophysiol. November 1, 2015; 114 (5): 3014-22.

Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32., Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM., J Biol Chem. July 10, 2015; 290 (28): 17074-84.

Cell communication across gap junctions: a historical perspective and current developments., Evans WH., Biochem Soc Trans. June 1, 2015; 43 (3): 450-9.

Loss of functional endothelial connexin40 results in exercise-induced hypertension in mice., Morton SK, Chaston DJ, Howitt L, Heisler J, Nicholson BJ, Fairweather S, Bröer S, Ashton AW, Matthaei KI, Hill CE., Hypertension. March 1, 2015; 65 (3): 662-9.

AMP-activated protein kinase α1 regulates cardiac gap junction protein connexin 43 and electrical remodeling following pressure overload., Alesutan I, Voelkl J, Stöckigt F, Mia S, Feger M, Primessnig U, Sopjani M, Munoz C, Borst O, Gawaz M, Pieske B, Metzler B, Heinzel F, Schrickel JW, Lang F., Cell Physiol Biochem. January 1, 2015; 35 (1): 406-18.

Carbon monoxide (CO) is a novel inhibitor of connexin hemichannels., León-Paravic CG, Figueroa VA, Guzmán DJ, Valderrama CF, Vallejos AA, Fiori MC, Altenberg GA, Reuss L, Retamal MA., J Biol Chem. December 26, 2014; 289 (52): 36150-7.

Activation, permeability, and inhibition of astrocytic and neuronal large pore (hemi)channels., Hansen DB, Ye ZC, Calloe K, Braunstein TH, Hofgaard JP, Ransom BR, Nielsen MS, MacAulay N., J Biol Chem. September 19, 2014; 289 (38): 26058-26073.

Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells., Figueroa VA, Retamal MA, Cea LA, Salas JD, Vargas AA, Verdugo CA, Jara O, Martínez AD, Sáez JC., Front Cell Neurosci. May 27, 2014; 8 265.                  

Connexin hemichannel and pannexin channel electrophysiology: how do they differ?, Patel D, Zhang X, Veenstra RD., FEBS Lett. April 17, 2014; 588 (8): 1372-8.

Distinct permeation profiles of the connexin 30 and 43 hemichannels., Hansen DB, Braunstein TH, Nielsen MS, MacAulay N., FEBS Lett. April 17, 2014; 588 (8): 1446-57.

Coregulation of multiple signaling mechanisms in pp60v-Src-induced closure of Cx43 gap junction channels., Mitra SS, Xu J, Nicholson BJ., J Membr Biol. August 1, 2012; 245 (8): 495-506.

Voltage-dependent conformational changes in connexin channels., Bargiello TA, Tang Q, Oh S, Kwon T., Biochim Biophys Acta. August 1, 2012; 1818 (8): 1807-22.

Connexins in epidermal homeostasis and skin disease., Scott CA, Tattersall D, O'Toole EA, Kelsell DP., Biochim Biophys Acta. August 1, 2012; 1818 (8): 1952-61.        

Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity., Ponsaerts R, De Vuyst E, Retamal M, D'hondt C, Vermeire D, Wang N, De Smedt H, Zimmermann P, Himpens B, Vereecke J, Leybaert L, Bultynck G., FASEB J. November 1, 2010; 24 (11): 4378-95.

Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue., Thibodeau IL, Xu J, Li Q, Liu G, Lam K, Veinot JP, Birnie DH, Jones DL, Krahn AD, Lemery R, Nicholson BJ, Gollob MH., Circulation. July 20, 2010; 122 (3): 236-44.

Functional analysis of hemichannels and gap-junctional channels formed by connexins 43 and 46., Hoang QV, Qian H, Ripps H., Mol Vis. July 15, 2010; 16 1343-52.              

Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains., Bouvier D, Spagnol G, Chenavas S, Kieken F, Vitrac H, Brownell S, Kellezi A, Forge V, Sorgen PL., J Biol Chem. December 4, 2009; 284 (49): 34257-71.

Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development., Rhee DY, Zhao XQ, Francis RJ, Huang GY, Mably JD, Lo CW., Development. September 1, 2009; 136 (18): 3185-93.          

Modulation of Cx46 hemichannels by nitric oxide., Retamal MA, Yin S, Altenberg GA, Reuss L., Am J Physiol Cell Physiol. June 1, 2009; 296 (6): C1356-63.

Conformational changes in a pore-forming region underlie voltage-dependent "loop gating" of an unapposed connexin hemichannel., Tang Q, Dowd TL, Verselis VK, Bargiello TA., J Gen Physiol. June 1, 2009; 133 (6): 555-70.                    

The cataract causing Cx50-S50P mutant inhibits Cx43 and intercellular communication in the lens epithelium., DeRosa AM, Meşe G, Li L, Sellitto C, Brink PR, Gong X, White TW., Exp Cell Res. April 1, 2009; 315 (6): 1063-75.

TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways., Tacheau C, Fontaine J, Loy J, Mauviel A, Verrecchia F., J Cell Physiol. December 1, 2008; 217 (3): 759-68.

Charges dispersed over the permeation pathway determine the charge selectivity and conductance of a Cx32 chimeric hemichannel., Oh S, Verselis VK, Bargiello TA., J Physiol. May 15, 2008; 586 (10): 2445-61.

H,K-ATPase protein localization and Kir4.1 function reveal concordance of three axes during early determination of left-right asymmetry., Aw S, Adams DS, Qiu D, Levin M., Mech Dev. January 1, 2008; 125 (3-4): 353-72.    

Taurine suppresses the spread of cell death in electrically coupled RPE cells., Udawatte C, Qian H, Mangini NJ, Kennedy BG, Ripps H., Mol Vis. January 1, 2008; 14 1940-50.          

Implication of gap junction coupling in amphibian vitellogenin uptake., Mónaco ME, Villecco EI, Sánchez SS., Zygote. May 1, 2007; 15 (2): 149-57.

Effect of charge substitutions at residue his-142 on voltage gating of connexin43 channels., Shibayama J, Gutiérrez C, González D, Kieken F, Seki A, Carrión JR, Sorgen PL, Taffet SM, Barrio LC, Delmar M., Biophys J. December 1, 2006; 91 (11): 4054-63.

Molecular dynamics and in vitro analysis of Connexin43: A new 14-3-3 mode-1 interacting protein., Park DJ, Freitas TA, Wallick CJ, Guyette CV, Warn-Cramer BJ., Protein Sci. October 1, 2006; 15 (10): 2344-55.

Mutation of a conserved threonine in the third transmembrane helix of alpha- and beta-connexins creates a dominant-negative closed gap junction channel., Beahm DL, Oshima A, Gaietta GM, Hand GM, Smock AE, Zucker SN, Toloue MM, Chandrasekhar A, Nicholson BJ, Sosinsky GE., J Biol Chem. March 24, 2006; 281 (12): 7994-8009.

Connexin31 cannot functionally replace connexin43 during cardiac morphogenesis in mice., Zheng-Fischhöfer Q, Ghanem A, Kim JS, Kibschull M, Schwarz G, Schwab JO, Nagy J, Winterhager E, Tiemann K, Willecke K., J Cell Sci. February 15, 2006; 119 (Pt 4): 693-701.

Xenopus connexins: how frogs bridge the gap., de Boer TP, van der Heyden MA., Differentiation. September 1, 2005; 73 (7): 330-40.

Dominant negative effect of connexin33 on gap junctional communication is mediated by connexin43 sequestration., Fiorini C, Mograbi B, Cronier L, Bourget I, Decrouy X, Nebout M, Ferrua B, Malassine A, Samson M, Fénichel P, Segretain D, Pointis G., J Cell Sci. September 15, 2004; 117 (Pt 20): 4665-72.

The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities., Weber PA, Chang HC, Spaeth KE, Nitsche JM, Nicholson BJ., Biophys J. August 1, 2004; 87 (2): 958-73.

Gap junctions and the connexin protein family., Söhl G, Willecke K., Cardiovasc Res. May 1, 2004; 62 (2): 228-32.

Is the junctional uncoupling elicited in rat ventricular myocytes by some dephosphorylation treatments due to changes in the phosphorylation status of Cx43?, Hervé JC, Plaisance I, Loncarek J, Duthe F, Sarrouilhe D., Eur Biophys J. May 1, 2004; 33 (3): 201-10.

Molecular cloning, functional analysis, and RNA expression analysis of connexin45.6: a zebrafish cardiovascular connexin., Christie TL, Mui R, White TW, Valdimarsson G., Am J Physiol Heart Circ Physiol. May 1, 2004; 286 (5): H1623-32.

Functional expression in Xenopus oocytes of gap-junctional hemichannels formed by a cysteine-less connexin 43., Bao X, Chen Y, Reuss L, Altenberg GA., J Biol Chem. March 12, 2004; 279 (11): 9689-92.

Mechanism of regulation of the gap junction protein connexin 43 by protein kinase C-mediated phosphorylation., Bao X, Altenberg GA, Reuss L., Am J Physiol Cell Physiol. March 1, 2004; 286 (3): C647-54.

???pagination.result.page??? 1 2 3 ???pagination.result.next???