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Summary Expression Phenotypes Gene Literature (56) GO Terms (0) Nucleotides (152) Proteins (44) Interactants (271) Wiki
XB--974344

Papers associated with gys1



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Translational Control of Xenopus Oocyte Meiosis: Toward the Genomic Era., Meneau F, Dupré A, Jessus C, Daldello EM., Cells. June 19, 2020; 9 (6):             


Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development., Peuchen EH, Cox OF, Sun L, Hebert AS, Coon JJ, Champion MM, Dovichi NJ, Huber PW., Sci Rep. November 15, 2017; 7 (1): 15647.                          


Glycine transporters GlyT1 and GlyT2 are differentially modulated by glycogen synthase kinase 3β., Jiménez E, Núñez E, Ibáñez I, Zafra F, Aragón C, Giménez C., Neuropharmacology. February 1, 2015; 89 245-54.


Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells., Song J, McColl J, Camp E, Kennerley N, Mok GF, McCormick D, Grocott T, Wheeler GN, Münsterberg AE., Proc Natl Acad Sci U S A. May 20, 2014; 111 (20): 7337-42.


Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice., Tumova L, Pombinho AR, Vojtechova M, Stancikova J, Gradl D, Krausova M, Sloncova E, Horazna M, Kriz V, Machonova O, Jindrich J, Zdrahal Z, Bartunek P, Korinek V., Mol Cancer Ther. April 1, 2014; .


Wnt-dependent osteogenic commitment of bone marrow stromal cells using a novel GSK3β inhibitor., Cook DA, Fellgett SW, Pownall ME, O'Shea PJ, Genever PG., Stem Cell Res. March 1, 2014; 12 (2): 415-27.


Significant modulation of the hepatic proteome induced by exposure to low temperature in Xenopus laevis., Nagasawa K, Tanizaki Y, Okui T, Watarai A, Ueda S, Kato T., Biol Open. August 21, 2013; 2 (10): 1057-69.                  


Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies., Kim SE, Huang H, Zhao M, Zhang X, Zhang A, Semonov MV, MacDonald BT, Zhang X, Garcia Abreu J, Peng L, He X., Science. May 17, 2013; 340 (6134): 867-70.


Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis., Takeo S, Swanson SK, Nandanan K, Nakai Y, Aigaki T, Washburn MP, Florens L, Hawley RS., Proc Natl Acad Sci U S A. April 24, 2012; 109 (17): 6382-9.


Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2., Hikasa H, Sokol SY., J Biol Chem. April 8, 2011; 286 (14): 12093-100.


Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes., Taelman VF, Dobrowolski R, Plouhinec JL, Fuentealba LC, Vorwald PP, Gumper I, Sabatini DD, De Robertis EM., Cell. December 23, 2010; 143 (7): 1136-48.        


A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription., Ewan K, Pajak B, Stubbs M, Todd H, Barbeau O, Quevedo C, Botfield H, Young R, Ruddle R, Samuel L, Battersby A, Raynaud F, Allen N, Wilson S, Latinkic B, Workman P, McDonald E, Blagg J, Aherne W, Dale T., Cancer Res. July 15, 2010; 70 (14): 5963-73.


Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity., Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E., Sci Signal. May 11, 2010; 3 (121): ra37.


Stimulation of electrogenic glucose transport by glycogen synthase kinase 3., Rexhepaj R, Dërmaku-Sopjani M, Gehring EM, Sopjani M, Kempe DS, Föller M, Lang F., Cell Physiol Biochem. January 1, 2010; 26 (4-5): 641-6.


Identification of targets of the Wnt pathway destruction complex in addition to beta-catenin., Kim NG, Xu C, Gumbiner BM., Proc Natl Acad Sci U S A. March 31, 2009; 106 (13): 5165-70.


Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6., Wu G, Huang H, Garcia Abreu J, He X., PLoS One. January 1, 2009; 4 (3): e4926.              


Possible involvement of phosphatidylinositol 3-kinase, but not protein kinase B or glycogen synthase kinase 3beta, in progesterone-induced oocyte maturation in the Japanese brown frog, Rana japonica., Ota R, Suwa K, Kotani T, Mita K, Yamashita M., Zoolog Sci. July 1, 2008; 25 (7): 773-81.


Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6., MacDonald BT, Yokota C, Tamai K, Zeng X, He X., J Biol Chem. June 6, 2008; 283 (23): 16115-23.


Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling., Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Xu Y, Lee SJ, Lee J, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC., PLoS One. January 1, 2008; 3 (12): e4046.          


Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells., Sinner D, Kordich JJ, Spence JR, Opoka R, Rankin S, Rankin S, Lin SC, Jonatan D, Zorn AM, Wells JM., Mol Cell Biol. November 1, 2007; 27 (22): 7802-15.                


FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A., Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD., J Biol Chem. November 17, 2006; 281 (46): 35021-9.


Glial cell line-derived neurotrophic factor-mediated enteric neuronal survival involves glycogen synthase kinase-3beta phosphorylation and coupling with 14-3-3., Mwangi S, Anitha M, Fu H, Sitaraman SV, Srinivasan S., Neuroscience. November 17, 2006; 143 (1): 241-51.


Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation., Gutierrez GJ, Vögtlin A, Castro A, Ferby I, Salvagiotto G, Ronai Z, Lorca T, Nebreda AR., Nat Cell Biol. October 1, 2006; 8 (10): 1084-94.


Phosphatidylinositol 3-kinase signaling is involved in neurogenesis during Xenopus embryonic development., Peng Y, Jiang BH, Yang PH, Cao Z, Shi X, Lin MC, He ML, Kung HF., J Biol Chem. July 2, 2004; 279 (27): 28509-14.


Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3., Sarkissian M, Mendez R, Richter JD., Genes Dev. January 1, 2004; 18 (1): 48-61.


Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin., Ferkey DM, Kimelman D., J Biol Chem. May 3, 2002; 277 (18): 16147-52.


Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus., Jia J, Amanai K, Wang G, Tang J, Wang B, Jiang J., Nature. April 4, 2002; 416 (6880): 548-52.


Identification of the Axin and Frat binding region of glycogen synthase kinase-3., Fraser E, Young N, Dajani R, Franca-Koh J, Ryves J, Williams RS, Yeo M, Webster MT, Richardson C, Smalley MJ, Pearl LH, Harwood A, Dale TC., J Biol Chem. January 18, 2002; 277 (3): 2176-85.


Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A., Yamamoto H, Hinoi T, Michiue T, Fukui A, Usui H, Janssens V, Van Hoof C, Goris J, Asashima M, Kikuchi A., J Biol Chem. July 20, 2001; 276 (29): 26875-82.


Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway., Saitoh T, Moriwaki J, Koike J, Takagi A, Miwa T, Shiokawa K, Katoh M., Biochem Biophys Res Commun. March 2, 2001; 281 (3): 815-20.


Cloning, expression and nuclear localization of human NPM3, a member of the nucleophosmin/nucleoplasmin family of nuclear chaperones., Shackleford GM, Ganguly A, MacArthur CA., BMC Genomics. January 1, 2001; 2 8.            


Inhibition of Wnt signaling pathway by a novel axin-binding protein., Kadoya T, Kishida S, Fukui A, Hinoi T, Michiue T, Asashima M, Kikuchi A., J Biol Chem. November 24, 2000; 275 (47): 37030-7.


Glycogen synthase kinase 3beta negatively regulates both DNA-binding and transcriptional activities of heat shock factor 1., Xavier IJ, Mercier PA, McLoughlin CM, Ali A, Woodgett JR, Ovsenek N., J Biol Chem. September 15, 2000; 275 (37): 29147-52.


Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C., Chen RH, Ding WV, McCormick F., J Biol Chem. June 9, 2000; 275 (23): 17894-9.


New steps in the Wnt/beta-catenin signal transduction pathway., Sakanaka C, Sun TQ, Williams LT., Recent Prog Horm Res. January 1, 2000; 55 225-36.


Regulation of glycogen synthase kinase 3beta and downstream Wnt signaling by axin., Hedgepeth CM, Deardorff MA, Rankin K, Klein PS., Mol Cell Biol. October 1, 1999; 19 (10): 7147-57.


Phosphorylation and glycosylation of nucleoporins., Miller MW, Caracciolo MR, Berlin WK, Hanover JA., Arch Biochem Biophys. July 1, 1999; 367 (1): 51-60.


beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation., Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X., Proc Natl Acad Sci U S A. May 25, 1999; 96 (11): 6273-8.            


Xenopus axin interacts with glycogen synthase kinase-3 beta and is expressed in the anterior midbrain., Hedgepeth CM, Deardorff MA, Klein PS., Mech Dev. February 1, 1999; 80 (2): 147-51.    


Regulation of ribosomal S6 protein kinase-p90(rsk), glycogen synthase kinase 3, and beta-catenin in early Xenopus development., Torres MA, Eldar-Finkelman H, Krebs EG, Moon RT., Mol Cell Biol. February 1, 1999; 19 (2): 1427-37.


A novel role for glycogen synthase kinase-3 in Xenopus development: maintenance of oocyte cell cycle arrest by a beta-catenin-independent mechanism., Fisher DL, Morin N, Dorée M., Development. February 1, 1999; 126 (3): 567-76.


Nuclear glycogen and glycogen synthase kinase 3., Ragano-Caracciolo M, Berlin WK, Miller MW, Hanover JA., Biochem Biophys Res Commun. August 19, 1998; 249 (2): 422-7.


Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin., Itoh K, Krupnik VE, Sokol SY., Curr Biol. May 7, 1998; 8 (10): 591-4.      


Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos., Yamamoto H, Kishida S, Uochi T, Ikeda S, Koyama S, Asashima M, Kikuchi A., Mol Cell Biol. May 1, 1998; 18 (5): 2867-75.


Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells., Stambolic V, Ruel L, Woodgett JR., Curr Biol. December 1, 1996; 6 (12): 1664-8.


A molecular mechanism for the effect of lithium on development., Klein PS, Melton DA., Proc Natl Acad Sci U S A. August 6, 1996; 93 (16): 8455-9.


The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3., Yost C, Torres M, Miller JR, Huang E, Kimelman D, Moon RT., Genes Dev. June 15, 1996; 10 (12): 1443-54.  


Overexpression of Xgsk-3 disrupts anterior ectodermal patterning in Xenopus., Pierce SB, Kimelman D., Dev Biol. May 1, 1996; 175 (2): 256-64.          


Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B., Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA., Nature. December 1, 1995; 378 (6559): 785-9.


Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase., Itoh K, Tang TL, Neel BG, Sokol SY., Development. December 1, 1995; 121 (12): 3979-88.              

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