Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (50) GO Terms (9) Nucleotides (47) Proteins (31) Interactants (86) Wiki
XB--981143

Papers associated with slc6a4l



???displayGene.coCitedPapers???
1 ???displayGene.morpholinoPapers???

???pagination.result.count???

???pagination.result.page??? 1

Sort Newest To Oldest Sort Oldest To Newest

referenced by:

Flux coupling, not specificity, shapes the transport and phylogeny of SLC6 glycine transporters., Le Guellec B, Rousseau F, Bied M, Supplisson S., Proc Natl Acad Sci U S A. October 11, 2022; 119 (41): e2205874119.                                              

Anxiolytic and antidepressants' effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms., Nitzan K, David D, Franko M, Toledano R, Fidelman S, Tenenbaum YS, Blonder M, Armoza-Eilat S, Shamir A, Rehavi M, Ben-Chaim Y, Doron R., Transl Psychiatry. May 19, 2022; 12 (1): 208.

Molecular and functional characterization of the Gulf toadfish serotonin transporter SLC6A4., Amador MHB, McDonald MD., J Exp Biol. April 6, 2018; 221 (Pt 7):


N-Alkylated Analogs of 4-Methylamphetamine (4-MA) Differentially Affect Monoamine Transporters and Abuse Liability., Solis E, Partilla JS, Sakloth F, Ruchala I, Schwienteck KL, De Felice LJ, Eltit JM, Glennon RA, Negus SS, Baumann MH., Neuropsychopharmacology. September 1, 2017; 42 (10): 1950-1961.

The external gate of the human and Drosophila serotonin transporters requires a basic/acidic amino acid pair for 3,4-methylenedioxymethamphetamine (MDMA) translocation and the induction of substrate efflux., Sealover NR, Felts B, Kuntz CP, Jarrard RE, Hockerman GH, Lamb PW, Barker EL, Henry LK., Biochem Pharmacol. November 15, 2016; 120 46-55.

Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands., Andersen J, Ladefoged LK, Kristensen TN, Munro L, Grouleff J, Stuhr-Hansen N, Kristensen AS, Schiøtt B, Strømgaard K., ACS Chem Neurosci. October 19, 2016; 7 (10): 1406-1417.

Substrate and Inhibitor-Specific Conformational Changes in the Human Serotonin Transporter Revealed by Voltage-Clamp Fluorometry., Söderhielm PC, Andersen J, Munro L, Nielsen AT, Kristensen AS., Mol Pharmacol. October 1, 2015; 88 (4): 676-88.

Expression, sorting and transport studies for the orphan carrier SLC10A4 in neuronal and non-neuronal cell lines and in Xenopus laevis oocytes., Schmidt S, Moncada M, Burger S, Geyer J., BMC Neurosci. June 19, 2015; 16 35.                        

'Second-generation' mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function., Saha K, Partilla JS, Lehner KR, Seddik A, Stockner T, Holy M, Sandtner W, Ecker GF, Sitte HH, Baumann MH., Neuropsychopharmacology. May 1, 2015; 40 (6): 1321-31.

Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation., Pai VP, Lemire JM, Paré JF, Lin G, Chen Y, Levin M., J Neurosci. March 11, 2015; 35 (10): 4366-85.                    

A novel method for inducing nerve growth via modulation of host resting potential: gap junction-mediated and serotonergic signaling mechanisms., Blackiston DJ, Anderson GM, Rahman N, Bieck C, Levin M., Neurotherapeutics. January 1, 2015; 12 (1): 170-84.            

Stereoselective inhibition of serotonin transporters by antimalarial compounds., Beckman ML, Pramod AB, Perley D, Henry LK., Neurochem Int. July 1, 2014; 73 98-106.

Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range., Chernet BT, Levin M., Oncotarget. May 30, 2014; 5 (10): 3287-306.              

Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates., Baumann MH, Bulling S, Benaderet TS, Saha K, Ayestas MA, Partilla JS, Ali SF, Stockner T, Rothman RB, Sandtner W, Sitte HH., Neuropsychopharmacology. May 1, 2014; 39 (6): 1355-65.          

A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles., Walentek P, Bogusch S, Thumberger T, Vick P, Dubaissi E, Beyer T, Blum M, Schweickert A., Development. April 1, 2014; 141 (7): 1526-33.                        

Mifepristone modulates serotonin transporter function., Li C, Shan L, Li X, Wei L, Li D., Neural Regen Res. March 15, 2014; 9 (6): 646-52.          

A quantitative model of amphetamine action on the 5-HT transporter., Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Boehm S, Freissmuth M, Sitte HH., Br J Pharmacol. February 1, 2014; 171 (4): 1007-18.              

The two Na+ sites in the human serotonin transporter play distinct roles in the ion coupling and electrogenicity of transport., Felts B, Pramod AB, Sandtner W, Burbach N, Bulling S, Sitte HH, Henry LK., J Biol Chem. January 17, 2014; 289 (3): 1825-40.

Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model., Chernet BT, Levin M., Dis Model Mech. May 1, 2013; 6 (3): 595-607.                  

The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters., Bulling S, Schicker K, Zhang YW, Zhang YW, Steinkellner T, Stockner T, Gruber CW, Boehm S, Freissmuth M, Rudnick G, Sitte HH, Sandtner W., J Biol Chem. May 25, 2012; 287 (22): 18524-34.              

Expression of serotonergic system components during early Xenopus embryogenesis., Nikishin DA, Kremnyov SV, Konduktorova VV, Shmukler YB., Int J Dev Biol. January 1, 2012; 56 (5): 385-91.                          

A fluorescence displacement assay for antidepressant drug discovery based on ligand-conjugated quantum dots., Chang JC, Tomlinson ID, Warnement MR, Iwamoto H, DeFelice LJ, Blakely RD, Rosenthal SJ., J Am Chem Soc. November 9, 2011; 133 (44): 17528-31.

A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport., Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD., J Biol Chem. September 2, 2011; 286 (35): 30823-30836.

Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder., Bang-Andersen B, Ruhland T, Jørgensen M, Smith G, Frederiksen K, Jensen KG, Zhong H, Nielsen SM, Hogg S, Mørk A, Stensbøl TB., J Med Chem. May 12, 2011; 54 (9): 3206-21.

Biotin tethered homotryptamine derivatives: high affinity probes of the human serotonin transporter (hSERT)., Tomlinson ID, Iwamoto H, Blakely RD, Rosenthal SJ., Bioorg Med Chem Lett. March 15, 2011; 21 (6): 1678-82.

Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway., Blackiston D, Adams DS, Lemire JM, Lobikin M, Levin M., Dis Model Mech. January 1, 2011; 4 (1): 67-85.                

The N terminus of monoamine transporters is a lever required for the action of amphetamines., Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH., J Biol Chem. April 2, 2010; 285 (14): 10924-38.                      

Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin., Fontana AC, Sonders MS, Pereira-Junior OS, Knight M, Javitch JA, Rodrigues V, Amara SG, Mortensen OV., Eur J Pharmacol. August 15, 2009; 616 (1-3): 48-57.

Helix XI contributes to the entrance of the serotonin transporter permeation pathway., Torres-Altoro MI, White KJ, Rodríguez GJ, Nichols DE, Barker EL., Protein Sci. October 1, 2008; 17 (10): 1761-70.

Calcium/calmodulin-dependent kinase II regulates the interaction between the serotonin transporter and syntaxin 1A., Ciccone MA, Timmons M, Phillips A, Quick MW., Neuropharmacology. October 1, 2008; 55 (5): 763-70.

N,N-dimethyl-thioamphetamine and methyl-thioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents., Gobbi M, Funicello M, Gerstbrein K, Holy M, Moya PR, Sotomayor R, Forray MI, Gysling K, Paluzzi S, Bonanno G, Reyes-Parada M, Sitte HH, Mennini T., J Neurochem. June 1, 2008; 105 (5): 1770-80.

Acceleration of serotonin transporter transport-associated current by 3,4-methylenedioxymethamphetamine (MDMA) under acidic conditions., Yamauchi Y, Izumi T, Unemura K, Uenishi Y, Nakagawa T, Kaneko S., Neurosci Lett. November 27, 2007; 428 (2-3): 72-6.

Evidence for significant contribution of a newly identified monoamine transporter (PMAT) to serotonin uptake in the human brain., Zhou M, Engel K, Wang J., Biochem Pharmacol. January 1, 2007; 73 (1): 147-54.

Imaging GABAc receptors with ligand-conjugated quantum dots., Tomlinson ID, Gussin HA, Little DM, Warnement MR, Qian H, Pepperberg DR, Rosenthal SJ., J Biomed Biotechnol. January 1, 2007; 2007 76514.              

Voltage and ionic regulation of human serotonin transporter in Xenopus oocytes., Li C, Zhong H, Wang Y, Wang H, Yang Z, Zheng Y, Liu K, Liu Y., Clin Exp Pharmacol Physiol. November 1, 2006; 33 (11): 1088-92.

[Establishment of heterologous expression model of hSERT in Xenopus laevis oocytes]., Wang YY, Jin Z, Li CZ, Liu YM., Zhongguo Ying Yong Sheng Li Xue Za Zhi. November 1, 2005; 21 (4): 444-8.

Serotonin transporter function is an early step in left-right patterning in chick and frog embryos., Fukumoto T, Blakely R, Levin M., Dev Neurosci. January 1, 2005; 27 (6): 349-63.

R-citalopram functionally antagonises escitalopram in vivo and in vitro: evidence for kinetic interaction at the serotonin transporter., Stórustovu Sí, Sánchez C, Pörzgen P, Brennum LT, Larsen AK, Pulis M, Ebert B., Br J Pharmacol. May 1, 2004; 142 (1): 172-80.

Regulating the conducting states of a mammalian serotonin transporter., Quick MW., Neuron. October 30, 2003; 40 (3): 537-49.

Conserved tyrosine-147 plays a critical role in the ligand-gated current of the epithelial cation/amino acid transporter/channel CAATCH1., Stevens BR, Feldman DH, Liu Z, Harvey WR., J Exp Biol. August 1, 2002; 205 (Pt 16): 2545-53.

Early fluorescence signals detect transitions at mammalian serotonin transporters., Li M, Lester HA., Biophys J. July 1, 2002; 83 (1): 206-18.

Targeting cell surface receptors with ligand-conjugated nanocrystals., Rosenthal SJ, Tomlinson I, Adkins EM, Schroeter S, Adams S, Swafford L, McBride J, Wang Y, DeFelice LJ, Blakely RD., J Am Chem Soc. May 1, 2002; 124 (17): 4586-94.

Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor., Ramsey IS, DeFelice LJ., J Biol Chem. April 26, 2002; 277 (17): 14475-82.

Voltage-dependent transient currents of human and rat 5-HT transporters (SERT) are blocked by HEPES and ion channel ligands., Li M, Farley RA, Lester HA., FEBS Lett. February 27, 2002; 513 (2-3): 247-52.

A lithium-induced conformational change in serotonin transporter alters cocaine binding, ion conductance, and reactivity of Cys-109., Ni YG, Chen JG, Androutsellis-Theotokis A, Huang CJ, Moczydlowski E, Rudnick G., J Biol Chem. August 17, 2001; 276 (33): 30942-7.

A novel electrogenic amino acid transporter is activated by K+ or Na+, is alkaline pH-dependent, and is Cl--independent., Feldman DH, Harvey WR, Stevens BR., J Biol Chem. August 11, 2000; 275 (32): 24518-26.

Ionic interactions in the Drosophila serotonin transporter identify it as a serotonin channel., Petersen CI, DeFelice LJ., Nat Neurosci. July 1, 1999; 2 (7): 605-10.

Amino acid residues that control pH modulation of transport-associated current in mammalian serotonin transporters., Cao Y, Li M, Mager S, Lester HA., J Neurosci. October 1, 1998; 18 (19): 7739-49.

Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel., Galli A, Petersen CI, deBlaquiere M, Blakely RD, DeFelice LJ., J Neurosci. May 15, 1997; 17 (10): 3401-11.

???pagination.result.page??? 1