Papers associated with nav1

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	Characterization of Na+ currents regulating intrinsic excitability of optic tectal neurons., Thompson AC, Aizenman CD., Life Sci Alliance. January 1, 2024; 7 (1):
	Extracellular cysteine disulfide bond break at Cys122 disrupts PIP 2 -dependent Kir2.1 channel function and leads to arrhythmias in Andersen-Tawil Syndrome., Cruz FM, Macías Á, Moreno-Manuel AI, Gutiérrez LK, Vera-Pedrosa ML, Martínez-Carrascoso I, Pérez PS, Ruiz Robles JM, Bermúdez-Jiménez FJ, Díaz-Agustín A, Martínez de Benito F, Santiago SA, Braza-Boils A, Martín-Martínez M, Gutierrez-Rodríguez M, Bernal JA, Zorio E, Jiménez-Jaimez J, Jalife J., bioRxiv. June 8, 2023;
	Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors., Angsutararux P, Dutta AK, Marras M, Abella C, Mellor RL, Shi J, Nerbonne JM, Silva JR., J Gen Physiol. May 1, 2023; 155 (5):
	Coupling the Cardiac Voltage-Gated Sodium Channel to Channelrhodopsin-2 Generates Novel Optical Switches for Action Potential Studies., Vom Dahl C, Müller CE, Berisha X, Nagel G, Zimmer T., Membranes (Basel). September 20, 2022; 12 (10):
	Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity., Scalise S, Zannino C, Lucchino V, Lo Conte M, Scaramuzzino L, Cifelli P, D'Andrea T, Martinello K, Fucile S, Palma E, Gambardella A, Ruffolo G, Cuda G, Parrotta EI., Biomedicines. May 5, 2022; 10 (5):
	Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate., Brosnan RJ, Ramos K, Aguiar AJA, Cenani A, Knych HK., Pharmacology. January 1, 2022; 107 (3-4): 167-178.
	Functional modulation of the human voltage-gated sodium channel NaV1.8 by auxiliary β subunits., Nevin ST, Lawrence N, Nicke A, Lewis RJ, Adams DJ., Channels (Austin). December 1, 2021; 15 (1): 79-93.
	Identification of SCN5a p.C335R Variant in a Large Family with Dilated Cardiomyopathy and Conduction Disease., Sedaghat-Hamedani F, Rebs S, El-Battrawy I, Chasan S, Krause T, Haas J, Zhong R, Liao Z, Xu Q, Zhou X, Akin I, Zitron E, Frey N, Streckfuss-Bömeke K, Kayvanpour E., Int J Mol Sci. November 30, 2021; 22 (23):
	Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5., Galleano I, Harms H, Choudhury K, Khoo K, Delemotte L, Pless SA., Proc Natl Acad Sci U S A. August 17, 2021; 118 (33):
	Functional and Structural Characterization of ClC-1 and Nav1.4 Channels Resulting from CLCN1 and SCN4A Mutations Identified Alone and Coexisting in Myotonic Patients., Brenes O, Barbieri R, Vásquez M, Vindas-Smith R, Roig J, Romero A, Valle GD, Bermúdez-Guzmán L, Bertelli S, Pusch M, Morales F., Cells. February 11, 2021; 10 (2):
	Low-Resistance silver bromide electrodes for recording fast ion channel kinetics under voltage clamp conditions., Ågren R, Zeberg H., J Neurosci Methods. January 15, 2021; 348 108984.
	Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity., Kerth CM, Hautvast P, Körner J, Lampert A, Meents JE., J Biol Chem. January 1, 2021; 296 100227.
	Small cyclic sodium channel inhibitors., Peigneur S, da Costa Oliveira C, de Sousa Fonseca FC, McMahon KL, Mueller A, Cheneval O, Cristina Nogueira Freitas A, Starobova H, Dimitri Gama Duarte I, Craik DJ, Vetter I, de Lima ME, Schroeder CI, Tytgat J., Biochem Pharmacol. January 1, 2021; 183 114291.
	Heterologous functional expression of ascidian Nav1 channels and close relationship with the evolutionary ancestor of vertebrate Nav channels., Kawai T, Hashimoto M, Eguchi N, Nishino JM, Jinno Y, Mori-Kreiner R, Aspåker M, Chiba D, Ohtsuka Y, Kawanabe A, Nishino AS, Okamura Y., J Biol Chem. January 1, 2021; 296 100783.
	Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target NaV1.7., Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF., Biochem Pharmacol. November 1, 2020; 181 114080.
	Uncoupling sodium channel dimers restores the phenotype of a pain-linked Nav 1.7 channel mutation., Rühlmann AH, Körner J, Hausmann R, Bebrivenski N, Neuhof C, Detro-Dassen S, Hautvast P, Benasolo CA, Meents J, Machtens JP, Schmalzing G, Lampert A., Br J Pharmacol. October 1, 2020; 177 (19): 4481-4496.
	A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans., Zeberg H, Dannemann M, Sahlholm K, Tsuo K, Maricic T, Wiebe V, Hevers W, Robinson HPC, Kelso J, Pääbo S., Curr Biol. September 7, 2020; 30 (17): 3465-3469.e4.
	GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels., Montandon GG, Cassoli JS, Peigneur S, Verano-Braga T, Santos DMD, Paiva ALB, Moraes ÉR, Kushmerick C, Borges MH, Richardson M, Pimenta AMC, Kjeldsen F, Diniz MRV, Tytgat J, Lima ME., Biochimie. September 1, 2020; 176 138-149.
	Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing., Khoo KK, Galleano I, Gasparri F, Wieneke R, Harms H, Poulsen MH, Chua HC, Wulf M, Tampé R, Pless SA., Nat Commun. May 8, 2020; 11 (1): 2284.
	Action potentials in Xenopus oocytes triggered by blue light., Walther F, Feind D, Vom Dahl C, Müller CE, Kukaj T, Sattler C, Nagel G, Gao S, Zimmer T., J Gen Physiol. May 4, 2020; 152 (5):
	Carvacrol inhibits the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.3, Nav1.7, and Nav1.8 expressed in Xenopus oocytes with different potencies., Horishita T, Ogata Y, Horishita R, Fukui R, Moriwaki K, Ueno S, Yanagihara N, Uezono Y, Sudo Y, Minami K., J Pharmacol Sci. April 1, 2020; 142 (4): 140-147.
	Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms., Bohannon BM, de la Cruz A, Wu X, Jowais JJ, Perez ME, Dykxhoorn DM, Liin SI, Larsson HP., Elife. March 24, 2020; 9
	Gating control of the cardiac sodium channel Nav1.5 by its β3-subunit involves distinct roles for a transmembrane glutamic acid and the extracellular domain., Salvage SC, Zhu W, Habib ZF, Hwang SS, Irons JR, Huang CLH, Silva JR, Jackson AP., J Biol Chem. December 20, 2019; 294 (51): 19752-19763.
	The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier., Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR, MacKinnon R., Elife. November 1, 2019; 8
	Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations., Mason ER, Wu F, Patel RR, Xiao Y, Cannon SC, Cummins TR., eNeuro. October 16, 2019; 6 (5):
	Recombinant Production and Structure-Function Study of the Ts1 Toxin from the Brazilian Scorpion Tityus serrulatus., Shenkarev ZO, Shulepko MA, Peigneur S, Myshkin MY, Berkut AA, Vassilevski AA, Tytgat J, Lyukmanova EN, Kirpichnikov MP., Dokl Biochem Biophys. May 1, 2019; 484 (1): 9-12.
	Myasthenic congenital myopathy from recessive mutations at a single residue in NaV1.4., Elia N, Palmio J, Castañeda MS, Shieh PB, Quinonez M, Suominen T, Hanna MG, Männikkö R, Udd B, Cannon SC., Neurology. March 26, 2019; 92 (13): e1405-e1415.
	Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA., Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ., Cell Rep. March 26, 2019; 26 (13): 3522-3536.e5.
	Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors., Peigneur S, Cheneval O, Maiti M, Leipold E, Heinemann SH, Lescrinier E, Herdewijn P, De Lima ME, Craik DJ, Schroeder CI, Tytgat J., FASEB J. March 1, 2019; 33 (3): 3693-3703.
	Molecular basis involved in the blocking effect of antidepressant metergoline on C-type inactivation of Kv1.4 channel., Bai HW, Eom S, Yeom HD, Nguyen KVA, Lee J, Sohn SO, Lee JH., Neuropharmacology. March 1, 2019; 146 65-73.
	Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation., Zhu W, Mazzanti A, Voelker TL, Hou P, Moreno JD, Angsutararux P, Naegle KM, Priori SG, Silva JR., Circ Res. February 15, 2019; 124 (4): 539-552.
	Molecular charge associated with antiarrhythmic actions in a series of amino-2-cyclohexyl ester derivatives., Pugsley MK, Yong SL, Goldin AL, Hayes ES, Walker MJA., Eur J Pharmacol. February 5, 2019; 844 241-252.
	Loss-of-function of Nav1.8/D1639N linked to human pain can be rescued by lidocaine., Kaluza L, Meents JE, Hampl M, Rösseler C, Hautvast PAI, Detro-Dassen S, Hausmann R, Schmalzing G, Lampert A., Pflugers Arch. December 1, 2018; 470 (12): 1787-1801.
	A Xenopus oocyte model system to study action potentials., Corbin-Leftwich A, Small HE, Robinson HH, Villalba-Galea CA, Boland LM., J Gen Physiol. November 5, 2018; 150 (11): 1583-1593.
	Anesthetic-sensitive ion channel modulation is associated with a molar water solubility cut-off., Brosnan RJ, Pham TL., BMC Pharmacol Toxicol. September 14, 2018; 19 (1): 57.
	Phoneutria nigriventer Spider Toxin PnTx2-1 (δ-Ctenitoxin-Pn1a) Is a Modulator of Sodium Channel Gating., Peigneur S, Paiva ALB, Cordeiro MN, Borges MH, Diniz MRV, de Lima ME, Tytgat J., Toxins (Basel). August 21, 2018; 10 (9):
	BK channel inhibition by strong extracellular acidification., Zhou Y, Xia XM, Lingle CJ., Elife. July 2, 2018; 7
	The neurosteroid allopregnanolone sulfate inhibits Nav1.3 α subunit-containing voltage-gated sodium channels, expressed in Xenopus oocytes., Horishita T, Yanagihara N, Ueno S, Okura D, Horishita R, Minami T, Ogata Y, Sudo Y, Uezono Y, Kawasaki T., J Pharmacol Sci. May 1, 2018; 137 (1): 93-97.
	Spider toxin inhibits gating pore currents underlying periodic paralysis., Männikkö R, Shenkarev ZO, Thor MG, Berkut AA, Myshkin MY, Paramonov AS, Kulbatskii DS, Kuzmin DA, Sampedro Castañeda M, King L, Wilson ER, Lyukmanova EN, Kirpichnikov MP, Schorge S, Bosmans F, Hanna MG, Kullmann DM, Vassilevski AA., Proc Natl Acad Sci U S A. April 24, 2018; 115 (17): 4495-4500.
	Improving the characterization of calcium channel gating pore currents with Stac3., Chahine M., J Gen Physiol. March 5, 2018; 150 (3): 375-378.
	Antidepressants inhibit Nav1.3, Nav1.7, and Nav1.8 neuronal voltage-gated sodium channels more potently than Nav1.2 and Nav1.6 channels expressed in Xenopus oocytes., Horishita T, Yanagihara N, Ueno S, Okura D, Horishita R, Minami T, Ogata Y, Sudo Y, Uezono Y, Sata T, Kawasaki T., Naunyn Schmiedebergs Arch Pharmacol. December 1, 2017; 390 (12): 1255-1270.
	Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation., Peters CH, Yu A, Zhu W, Silva JR, Ruben PC., PLoS One. September 8, 2017; 12 (9): e0184605.
	Biophysical characterization of the Varroa destructor NaV1 sodium channel and its affinity for τ-fluvalinate insecticide., Gosselin-Badaroudine P, Chahine M., FASEB J. July 1, 2017; 31 (7): 3066-3071.
	Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes., Osteen JD, Sampson K, Iyer V, Julius D, Bosmans F., Proc Natl Acad Sci U S A. June 27, 2017; 114 (26): 6836-6841.
	Functional reconstitution of rat Nav1.6 sodium channels in vitro for studies of pyrethroid action., Soderlund DM, Tan J, He B., Neurotoxicology. May 1, 2017; 60 142-149.
	Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET., Kubota T, Durek T, Dang B, Finol-Urdaneta RK, Craik DJ, Kent SB, French RJ, Bezanilla F, Correa AM., Proc Natl Acad Sci U S A. March 7, 2017; 114 (10): E1857-E1865.
	Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains., Hsu EJ, Zhu W, Schubert AR, Voelker T, Varga Z, Silva JR., J Gen Physiol. March 6, 2017; 149 (3): 389-403.
	Mefloquine inhibits voltage dependent Nav1.4 channel by overlapping the local anaesthetic binding site., Paiz-Candia B, Islas AA, Sánchez-Solano A, Mancilla-Simbro C, Scior T, Millan-PerezPeña L, Salinas-Stefanon EM., Eur J Pharmacol. February 5, 2017; 796 215-223.
	Amyloid precursor protein modulates Nav1.6 sodium channel currents through a Go-coupled JNK pathway., Li S, Wang X, Ma QH, Yang WL, Zhang XG, Dawe GS, Xiao ZC., Sci Rep. December 23, 2016; 6 39320.
	Electrophysiological characterization of a large set of novel variants in the SCN5A-gene: identification of novel LQTS3 and BrS mutations., Ortiz-Bonnin B, Rinné S, Moss R, Streit AK, Scharf M, Richter K, Stöber A, Pfeufer A, Seemann G, Kääb S, Beckmann BM, Decher N., Pflugers Arch. August 1, 2016; 468 (8): 1375-87.

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