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Summary Expression Phenotypes Gene Literature (22) GO Terms (7) Nucleotides (129) Proteins (66) Interactants (62) Wiki
XB--992874

Papers associated with wrn



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Ligand binding characteristics of the Ku80 von Willebrand domain., Kim K, Min J, Kirby TW, Gabel SA, Pedersen LC, London RE., DNA Repair (Amst). January 1, 2020; 85 102739.

Dna2 initiates resection at clean DNA double-strand breaks., Paudyal SC, Li S, Yan H, Hunter T, You Z., Nucleic Acids Res. November 16, 2017; 45 (20): 11766-11781.            

Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection., Zadorozhny K, Sannino V, Beláň O, Mlčoušková J, Špírek M, Costanzo V, Krejčí L., Cell Rep. October 10, 2017; 21 (2): 333-340.                

The N-terminus of RPA large subunit and its spatial position are important for the 5'->3' resection of DNA double-strand breaks., Tammaro M, Liao S, McCane J, Yan H., Nucleic Acids Res. October 15, 2015; 43 (18): 8790-800.                  

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres., Badie S, Carlos AR, Folio C, Okamoto K, Bouwman P, Jonkers J, Tarsounas M., EMBO J. February 3, 2015; 34 (3): 410-24.              

Analysis of MRE11's function in the 5'-->3' processing of DNA double-strand breaks., Liao S, Guay C, Toczylowski T, Yan H., Nucleic Acids Res. May 1, 2012; 40 (10): 4496-506.                

Mechanistic analysis of Xenopus EXO1's function in 5'-strand resection at DNA double-strand breaks., Liao S, Toczylowski T, Yan H., Nucleic Acids Res. August 1, 2011; 39 (14): 5967-77.                

Replication protein A promotes 5'-->3' end processing during homology-dependent DNA double-strand break repair., Yan H, Toczylowski T, McCane J, Chen C, Liao S., J Cell Biol. January 24, 2011; 192 (2): 251-61.              

Roles of Werner syndrome protein in protection of genome integrity., Rossi ML, Ghosh AK, Bohr VA., DNA Repair (Amst). March 2, 2010; 9 (3): 331-44.

Identification of the Xenopus DNA2 protein as a major nuclease for the 5'->3' strand-specific processing of DNA ends., Liao S, Toczylowski T, Yan H., Nucleic Acids Res. November 1, 2008; 36 (19): 6091-100.              

Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks., Sallmyr A, Tomkinson AE, Rassool FV., Blood. August 15, 2008; 112 (4): 1413-23.

Ku80 removal from DNA through double strand break-induced ubiquitylation., Postow L, Ghenoiu C, Woo EM, Krutchinsky AN, Chait BT, Funabiki H., J Cell Biol. August 11, 2008; 182 (3): 467-79.                

The role of WRN in DNA repair is affected by post-translational modifications., Kusumoto R, Muftuoglu M, Bohr VA., Mech Ageing Dev. January 1, 2007; 128 (1): 50-7.

Mechanistic analysis of a DNA end processing pathway mediated by the Xenopus Werner syndrome protein., Toczylowski T, Yan H., J Biol Chem. November 3, 2006; 281 (44): 33198-205.

Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest., Sasakawa N, Fukui T, Waga S., J Biochem. July 1, 2006; 140 (1): 95-103.

Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair., Yan H, McCane J, Toczylowski T, Chen C., J Cell Biol. October 24, 2005; 171 (2): 217-27.              

Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases., Doherty KM, Sommers JA, Gray MD, Lee JW, Lee JW, von Kobbe C, Thoma NH, Kureekattil RP, Kenny MK, Brosh RM., J Biol Chem. August 19, 2005; 280 (33): 29494-505.

Evidence for a replication function of FFA-1, the Xenopus orthologue of Werner syndrome protein., Chen CY, Graham J, Yan H., J Cell Biol. March 5, 2001; 152 (5): 985-96.                

Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex., Dimitrova DS, Todorov IT, Melendy T, Gilbert DM., J Cell Biol. August 23, 1999; 146 (4): 709-22.                    

Replication focus-forming activity 1 and the Werner syndrome gene product., Yan H, Chen CY, Kobayashi R, Newport J., Nat Genet. August 1, 1998; 19 (4): 375-8.

FFA-1, a protein that promotes the formation of replication centers within nuclei., Yan H, Newport J., Science. September 29, 1995; 269 (5232): 1883-5.

A single-cell analysis of early retinal ganglion cell differentiation in Xenopus: from soma to axon tip., Holt CE., J Neurosci. September 1, 1989; 9 (9): 3123-45.                                

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