wnt3a Phenotypes

Summary

Expression

Phenotypes

Gene Literature (225)

XB-GENEPAGE-1217287

Gene Symbol: wnt3a Gene Name: Wnt family member 3A

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
duplicated main body axis (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: wnt3a manipulated (4 sources), wnt3a assayed (1 source)
Computed annotations: wnt3a assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + wnt3a (1 source), Xla Wt + wnt3a + animal cap explant (1 source), Xla Wt + wnt3a + animal cap explant (1 source), Xla Wt + wnt3a + chd1 + animal cap explant (1 source), Xla Wt + wnt3a + fermt2 MO + animal cap explant (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (46 sources): abnormal caudal vertebrae morphology, abnormal cerebral cortex morphology, abnormal cervical axis morphology, abnormal cervical vertebrae morphology, abnormal cortical marginal zone morphology, abnormal gastrulation, abnormal mesoderm development, abnormal rostral-caudal axis patterning, abnormal somite development, abnormal suckling behavior, abnormal tail bud morphology, abnormal tailgut morphology, abnormal tail morphology, abnormal thoracic vertebrae morphology, abnormal urination, absent Cajal-Retzius cell, absent choroid plexus, absent hindlimb, absent sacral vertebrae, absent tail, absent tail bud, caudal body truncation, cervical vertebral transformation, decreased body length, decreased Cajal-Retzius cell number, decreased caudal vertebrae number, decreased embryo size, decreased lumbar vertebrae number, decreased thoracic vertebrae number, decreased ventral ectodermal ridge size, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, failure of somite differentiation, hindlimb paralysis, incomplete somite formation, kinked neural tube, lumbar vertebral transformation, nervous system phenotype, postnatal lethality, premature death, reduced female fertility, sacral vertebral transformation, short mandible, thoracic vertebral transformation, truncated notochord, vestigial tail [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (46 sources): abnormal caudal vertebrae morphology, abnormal cerebral cortex morphology, abnormal cervical axis morphology, abnormal cervical vertebrae morphology, abnormal cortical marginal zone morphology, abnormal gastrulation, abnormal mesoderm development, abnormal rostral-caudal axis patterning, abnormal somite development, abnormal suckling behavior, [+]