tcf15 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-488934

Gene Symbol: tcf15 Gene Name: transcription factor 15

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal anterior-posterior axis, curved lateral (3 sources), abnormally disorganized myotome (2 sources), abnormally irregular spatial pattern of somite (2 sources), abnormally localised myotome (2 sources), abnormally localised nucleus in myotome (2 sources), decreased length of anterior-posterior axis (2 sources), abnormal anterior-posterior axis morphology (1 source), abnormal dermatome morphology (1 source), abnormally decreased number of somite (1 source), abnormally localised mesodermal cell (1 source), abnormal somite morphology (1 source), abnormal somitogenesis (1 source), fused somites (1 source), increased length of the anterior-posterior axis (1 source), increased length of the somite (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal anterior-posterior axis, curved lateral (3 sources), abnormally disorganized myotome (2 sources), abnormally irregular spatial pattern of somite (2 sources), abnormally localised myotome (2 sources), abnormally localised nucleus in myotome (2 sources), decreased length of anterior-posterior axis (2 sources), abnormal anterior-posterior axis morphology (1 source), abnormal dermatome morphology (1 source), abnormally decreased number of somite (1 source), abnormally localised mesodermal cell (1 source), abnormal somite morphology (1 source), abnormal somitogenesis (1 source), fused somites (1 source), increased length of the anterior-posterior axis (1 source), increased length of the somite (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tcf15 manipulated (6 sources), tcf15 assayed (1 source)
Computed annotations: tcf15 assayed (10 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + tcf15-GR + DEX (5 sources), Xla Wt + tcf15 MO (3 sources), Xla Wt + dntcf15-GR + DEX (2 sources), Xla Wt + tcf15 MO (2 sources), Xla Wt + dntcf15-GR + DEX (1 source), Xla Wt + tcf15 MO (1 source), Xla Wt + tcf15 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal abdominal wall morphology, abnormal basioccipital bone morphology, abnormal costovertebral joint morphology, abnormal craniofacial bone morphology, abnormal exoccipital bone morphology, abnormal intercostal muscle morphology, abnormal limb posture, abnormal paraxial mesoderm morphology, abnormal skeletal muscle morphology, abnormal spine curvature, abnormal sternocostal joint morphology, abnormal sternum ossification, abnormal supraoccipital bone morphology, absent dermatome, absent myotome, absent sclerotome, aphagia, caudal body truncation, curly tail, fusion of atlas and occipital bones, impaired somite development, neonatal lethality, complete penetrance, short rostral-caudal axis, short tail [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal abdominal wall morphology, abnormal basioccipital bone morphology, abnormal costovertebral joint morphology, abnormal craniofacial bone morphology, abnormal exoccipital bone morphology, abnormal intercostal muscle morphology, abnormal limb posture, abnormal paraxial mesoderm morphology, abnormal skeletal muscle morphology, abnormal spine curvature, [+]