txn2 Phenotypes

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PhenotypesPheno.

Gene Literature (2)Lit. (2)

GO Terms (18)GO (18)

Nucleotides (317)Nucl. (317)

Proteins (45)Prot. (45)

Interactants (209)Interact. (209)

XB-GENEPAGE-943372

Gene Symbol: txn2 Gene Name: thioredoxin 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: txn2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (22 sources): Abnormal autonomic nervous system physiology, Abnormal muscle tone, Axonal degeneration, Bilateral tonic-clonic seizure, Decreased activity of mitochondrial complex I, Decreased activity of mitochondrial complex III, Delayed myelination, Diffuse cerebellar atrophy, Gastrointestinal dysmotility, Gastrojejunal tube feeding in infancy, Global brain atrophy, Increased circulating lactate concentration, Increased CSF lactate, Increased CSF protein concentration, Myoclonic spasms, Neurodegeneration, obsolete Poor coordination, Optic neuropathy, Primary microcephaly, Retinopathy, Severe global developmental delay, Subependymal cysts [+]
Mouse (5 sources): abnormal cellular respiration, decreased embryo size, embryonic lethality during organogenesis, complete penetrance, incomplete rostral neuropore closure, increased embryonic tissue cell apoptosis
View all ortholog results at Monarch