abnormal interdigital cell death, abnormal intersomitic vessel morphology, abnormal notochord morphology, abnormal pancreas development, abnormal pancreatic beta cell differentiation, abnormal paraxial mesoderm morphology, abnormal rostral-caudal axis patterning, abnormal somite shape, abnormal vascular regression, abnormal visceral yolk sac morphology, abnormal vitelline vascular remodeling, abnormal vitelline vasculature morphology, absent intersomitic vessels, absent pancreatic duct, absent second pharyngeal arch, absent vitelline blood vessels, cardiovascular system phenotype, caudal body truncation, decreased body size, decreased hair follicle number, distended pericardium, embryonic growth retardation, embryonic lethality, embryonic lethality during organogenesis, complete penetrance, epidermal cyst, failure of chorioallantoic fusion, failure of heart looping, failure of somite differentiation, fused phalanges, fused somites, incomplete somite formation, kinked neural tube, pericardial edema, poor arterial differentiation, premature death, premature hair loss, premature neuronal precursor differentiation, reduced cerebellar foliation, small cerebellum, small heart