ago2 Phenotypes

Phenotypes

XB-GENEPAGE-1001915

Gene Symbol: ago2 Gene Name: argonaute 2, RISC catalytic component

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ago2 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (30 sources): abnormal embryonic tissue morphology, abnormal erythropoiesis, abnormal forebrain development, abnormal pancreatic beta cell morphology, abnormal placenta morphology, abnormal proerythroblast morphology, abnormal visceral yolk sac morphology, cellular phenotype, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased mean corpuscular hemoglobin, decreased mean corpuscular volume, decreased pancreatic beta cell mass, decreased pancreatic beta cell proliferation, embryonic growth arrest, embryonic growth retardation, embryonic lethality between implantation and somite formation, complete penetrance, endocrine/exocrine gland phenotype, homeostasis/metabolism phenotype, improved glucose tolerance, increased number of Heinz bodies, increased red blood cell distribution width, neonatal lethality, complete penetrance, no abnormal phenotype detected, open neural tube, pericardial edema, placental labyrinth hypoplasia, prenatal lethality, complete penetrance, wavy neural tube [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (30 sources): abnormal embryonic tissue morphology, abnormal erythropoiesis, abnormal forebrain development, abnormal pancreatic beta cell morphology, abnormal placenta morphology, abnormal proerythroblast morphology, abnormal visceral yolk sac morphology, cellular phenotype, decreased erythrocyte cell number, decreased hematocrit, [+]