Monarch Ortholog Phenotypes
|
Human (10 sources):
Absent speech,
Cerebral hypomyelination,
Epileptic encephalopathy,
Global developmental delay,
Hyperreflexia,
Myopia,
Reduced eye contact,
Seizure,
Severe muscular hypotonia,
Spasticity
|
Mouse (22 sources):
abnormal aerobic respiration,
abnormal cellular respiration,
abnormal dopamine level,
abnormal GABAergic neuron morphology,
abnormal synaptic dopamine release,
convulsive seizures,
decreased gamma-aminobutyric acid level,
decreased serotonin level,
decreased striatum size,
enhanced behavioral response to amphetamine,
enlarged lateral ventricles,
hunched posture,
hyperresponsive,
impaired balance,
impaired limb coordination,
increased anxiety-related response,
increased taurine level,
increased thigmotaxis,
increased vertical activity,
limb grasping,
oxidative stress,
postnatal lethality, complete penetrance
[+]
|
View all ortholog results at Monarch
|