ppargc1b Phenotypes

Phenotypes

XB-GENEPAGE-1004402

Gene Symbol: ppargc1b Gene Name: peroxisome proliferator-activated receptor gamma, coactivator 1 beta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ppargc1b assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (37 sources): abnormal brown adipose tissue morphology, abnormal brown fat cell morphology, abnormal fat cell morphology, abnormal mitochondrial physiology, abnormal osteoclast differentiation, abnormal oxidative phosphorylation, abnormal respiratory electron transport chain, abnormal skeletal muscle fiber type ratio, abnormal skeletal muscle morphology, abnormal white adipose tissue morphology, adipose tissue phenotype, behavior/neurological phenotype, cardiovascular system phenotype, decreased brown fat lipid droplet number, decreased circulating free fatty acids level, decreased gonadal fat pad weight, decreased oxygen consumption, decreased skeletal muscle fiber size, decreased survivor rate, decreased triglyceride level, decreased white adipose tissue amount, enhanced exercise endurance, growth/size/body region phenotype, homeostasis/metabolism phenotype, hypoactivity, impaired adaptive thermogenesis, impaired exercise endurance, increased brown adipose tissue amount, increased brown fat cell lipid droplet size, increased liver triglyceride level, increased liver weight, increased white fat cell size, macrovesicular hepatic steatosis, muscle phenotype, postnatal lethality, postnatal lethality, incomplete penetrance, skeletal muscle hypoplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (37 sources): abnormal brown adipose tissue morphology, abnormal brown fat cell morphology, abnormal fat cell morphology, abnormal mitochondrial physiology, abnormal osteoclast differentiation, abnormal oxidative phosphorylation, abnormal respiratory electron transport chain, abnormal skeletal muscle fiber type ratio, abnormal skeletal muscle morphology, abnormal white adipose tissue morphology, [+]