| Monarch Ortholog Phenotypes
|
Human (45 sources):
Abnormal circulating glutamine concentration,
Abnormal clitoris morphology,
Abnormal facial shape,
Abnormal respiratory system physiology,
Abnormality of the kidney,
Anemia,
Asthma,
Atrial septal defect,
Biventricular hypertrophy,
Cirrhosis,
Clitoral hypertrophy,
Coarctation of aorta,
Decreased liver function,
Deep philtrum,
Depressed nasal bridge,
Edema,
Failure to thrive,
Global developmental delay,
Hepatic fibrosis,
Hepatomegaly,
Hepatosplenomegaly,
Hydrops fetalis,
Increased serum bile acid concentration,
Intrauterine growth retardation,
Low-set ears,
Micronodular cirrhosis,
Oligohydramnios,
Pancytopenia,
Patent ductus arteriosus,
Patent foramen ovale,
Poor suck,
Premature skin wrinkling,
Proteinuria,
Short neck,
Short philtrum,
Small for gestational age,
Splenomegaly,
Synophrys,
Telangiectasia,
Thin vermilion border,
Thrombocytopenia,
Triangular face,
Ventricular septal defect,
Wide anterior fontanel,
Wide mouth
[+]
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|
Mouse (7 sources):
abnormal nucleotide metabolism,
abnormal sperm mitochondrial sheath morphology,
abnormal sperm physiology,
asthenozoospermia,
impaired acrosome reaction,
impaired fertilization,
reduced male fertility
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.