npr3 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-1012469

Gene Symbol: npr3 Gene Name: natriuretic peptide receptor 3

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
increased apoptosis in ectoderm (1 source), increased cell population proliferation (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: npr3 manipulated (2 sources), npr3 assayed (2 sources)
Computed annotations: npr3 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + npr3 MO (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (53 sources): abnormal abdominal fat pad morphology, abnormal adipose tissue distribution, abnormal blood homeostasis, abnormal bone remodeling, abnormal caudal vertebrae morphology, abnormal interscapular fat pad morphology, abnormal intervertebral disk development, abnormal long bone epiphyseal plate proliferative zone, abnormal metacarpal bone morphology, abnormal nucleus pulposus morphology, abnormal osteoclast morphology, abnormal phalanx morphology, abnormal sacral vertebrae morphology, abnormal skeleton development, abnormal urine nucleotide level, abnormal vertebrae development, abnormal vertebral column morphology, abnormal vertebral epiphyseal plate morphology, absent nucleus pulposus, caudal hemivertebra, caudal vertebral fusion, craniofacial phenotype, decreased brown fat cell lipid droplet size, decreased epididymal fat pad weight, decreased inguinal fat pad weight, decreased interscapular fat pad weight, decreased retroperitoneal fat pad weight, decreased urine osmolality, decreased white fat cell size, delayed bone ossification, delayed endochondral bone ossification, domed cranium, elongated metatarsal bones, elongated vertebral body, elongated vertebral column, hunched posture, increased body length, increased bone mineral content, increased circulating alkaline phosphatase level, increased erythrocyte cell number, increased length of long bones, increased or absent threshold for auditory brainstem response, increased osteoblast cell number, increased thoracic vertebrae number, increased width of hypertrophic chondrocyte zone, kinked tail, long tail, postnatal lethality, incomplete penetrance, premature death, reduced fertility, small thoracic cage, thin body, vision/eye phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (53 sources): abnormal abdominal fat pad morphology, abnormal adipose tissue distribution, abnormal blood homeostasis, abnormal bone remodeling, abnormal caudal vertebrae morphology, abnormal interscapular fat pad morphology, abnormal intervertebral disk development, abnormal long bone epiphyseal plate proliferative zone, abnormal metacarpal bone morphology, abnormal nucleus pulposus morphology, [+]