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Summary Expression Phenotypes Gene Literature (63) GO Terms (3) Nucleotides (289) Proteins (40) Interactants (1106) Wiki

aldh1a2     aldehyde dehydrogenase 1 family member A2

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally anteriorly mislocalised eye (4 sources), abnormally incomplete structure of head (4 sources), absent eye (4 sources), decreased length of anterior-posterior axis (4 sources), fused eyes (4 sources), abnormal mouth morphology (2 sources), abnormal roof of mouth morphology (2 sources), abnormal craniofacial region morphology (1 source), abnormal eye morphology (1 source), abnormal head morphology (1 source), abnormally decreased volume of oral cavity (1 source), decreased size of the head mesenchyme (1 source), decreased size of the intercanthal region (1 source), decreased size of the mouth (1 source), decreased width of the head (1 source), decreased width of the mouth (1 source), increased pigmentation in the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: aldh1a2 manipulated (1 source), aldh1a2 assayed (9 sources)
Computed annotations: aldh1a2 assayed (8 sources)
Diseases from the human disease ontology (DO) manually associated with phenotypes from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
orofacial cleft (1AP source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + aldh1a2 MO (3 sources), Xla Wt + aldh1a2 + retinol (1 source), Xla Wt + aldh1a2 + retinol (1 source), Xla Wt + aldh1a2 + sdr16c5 + retinol (1 source), Xla Wt + aldh1a2 + sdr16c5 + retinol (1 source), Xla Wt + aldh1a2 MO (1 source), Xla Wt + aldh1a2 MO + rdh10 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Ischemic stroke
Mouse (75 sources): aberrant origin of the right subclavian artery, abnormal aortic arch and aortic arch branch attachment, abnormal artery morphology, abnormal common carotid artery morphology, abnormal embryo turning, abnormal embryonic tissue morphology, abnormal fetal atrioventricular canal morphology, abnormal fetal cardiomyocyte morphology, abnormal first pharyngeal arch morphology, abnormal glossopharyngeal ganglion morphology, [+]

View all ortholog results at Monarch