pak4 Phenotypes

XB-GENEPAGE-1013748

Gene Symbol: pak4 Gene Name: p21 protein (Cdc42/Rac)-activated kinase 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pak4 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (21 sources): abnormal axon extension, abnormal cell adhesion, abnormal nervous system development, abnormal neuron differentiation, abnormal placenta labyrinth morphology, abnormal placenta vasculature, abnormal spinal cord interneuron morphology, abnormal visceral yolk sac morphology, abnormal vitelline vascular remodeling, decreased cell proliferation, decreased embryo size, decreased embryonic neuroepithelium thickness, dilated heart, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, increased apoptosis, pale placenta, pale yolk sac, preweaning lethality, complete penetrance, thin myocardium, thin ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (21 sources): abnormal axon extension, abnormal cell adhesion, abnormal nervous system development, abnormal neuron differentiation, abnormal placenta labyrinth morphology, abnormal placenta vasculature, abnormal spinal cord interneuron morphology, abnormal visceral yolk sac morphology, abnormal vitelline vascular remodeling, decreased cell proliferation, [+]