kdm5c Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (348)

Interactants (49)

XB-GENEPAGE-1033024

Gene Symbol: kdm5c Gene Name: lysine demethylase 5C

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: kdm5c manipulated (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + kdm5c MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (54 sources): Aggressive behavior, Autism, Babinski sign, Brachydactyly, Camptodactyly of finger, Clinodactyly, Cryptorchidism, Decreased testicular size, Deeply set eye, Delayed speech and language development, Diastema, Distal lower limb amyotrophy, Facial hypotonia, Furrowed tongue, High palate, High, narrow palate, Hypermetropia, Hyperreflexia, Hypoplasia of the maxilla, Intellectual disability, progressive, Intellectual disability, severe, Large hands, Low frustration tolerance, Lower limb hyperreflexia, Lower limb hypertonia, Macrocephaly, Macrotia, Mandibular prognathia, Microcephaly, Micrognathia, Micropenis, Multiple cafe-au-lait spots, Myopia, Pectus excavatum, Progressive spastic paraplegia, Prominent nasal bridge, Protruding ear, Restlessness, Seizure, Short distal phalanx of finger, Short foot, Short palm, Short stature, Shuffling gait, Small forehead, Smooth philtrum, Spasticity, Strabismus, Talipes calcaneovarus, Talipes equinovarus, Tapered finger, Thin upper lip vermilion, Upslanted palpebral fissure, obsolete Alopecia areata [+]
Mouse (15 sources): abnormal dendritic mushroom spine morphology, abnormal dendritic spine morphology, abnormal developmental patterning, abnormal impulsive behavior control, abnormal pyramidal neuron dendrite morphology, abnormal social investigation, decreased anxiety-related response, decreased body size, decreased dendritic spine density, impaired contextual conditioning behavior, impaired cued conditioning behavior, impaired spatial learning, increased aggression towards mice, no abnormal phenotype detected, reproductive system phenotype [+]
View all ortholog results at Monarch