foxh1 Phenotypes

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Phenotypes

Gene Literature (53)

Nucleotides (209)

Interactants (636)

XB-GENEPAGE-1194371

Gene Symbol: foxh1 Gene Name: forkhead box H1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: foxh1 manipulated (5 sources), foxh1 assayed (1 source)
Computed annotations: foxh1 assayed (6 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + foxh1-EnR (1 source), Xla Wt + foxh1 mKD (1 source), Xla Wt + foxh1 + smad2 (1 source), Xla Wt + foxh1-VP16 (1 source), Xla Wt + foxh1-VP16-GR + DEX (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (35 sources): Abnormal cardiovascular system morphology, Agenesis of corpus callosum, Ambiguous genitalia, Anteverted nares, Asthma, Choanal atresia, Cleft palate, Cyclopia, Duodenal atresia, EMG: myopathic abnormalities, Hemangioma, Holoprosencephaly, Hypoplasia of penis, Hypotelorism, Hypothyroidism, Intellectual disability, Intrauterine growth retardation, Iris coloboma, Maternal diabetes, Microcephaly, Midnasal stenosis, Narrow nasal bridge, Orofacial cleft, Panhypopituitarism, Premature birth, Renal agenesis, Scoliosis, Seizure, Short nose, Short philtrum, Short stature, Solitary median maxillary central incisor, Strabismus, Tented upper lip vermilion, Tetralogy of Fallot [+]
Mouse (43 sources): abdominal situs ambiguus, abnormal anterior head development, abnormal anterior primitive streak morphology, abnormal azygos vein morphology, abnormal cardiac outflow tract development, abnormal cranium morphology, abnormal heart development, abnormal heart looping, abnormal heart position or orientation, abnormal hepatic portal vein morphology, abnormal mesendoderm development, abnormal neural plate morphology, abnormal pericardial cavity morphology, abnormal pharyngeal arch artery morphology, abnormal renal vein morphology, abnormal right subclavian artery morphology, abnormal sternum morphology, abnormal thoracic cavity morphology, absent heart right ventricle, absent mandible, absent neural folds, absent notochord, absent pericardium, absent prechordal mesoderm, absent primitive node, decreased embryo size, disorganized myocardium, double outlet right ventricle, Taussig bing type, double outlet right ventricle with atrioventricular septal defect, embryonic-extraembryonic boundary constriction, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, failure of heart looping, fused somites, heart left ventricle hypoplasia, no abnormal phenotype detected, pericardial edema, postnatal lethality, complete penetrance, right pulmonary isomerism, right-sided isomerism, right-sided stomach, situs inversus with levocardia, trabecula carnea hypoplasia [+]
View all ortholog results at Monarch