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Summary Expression Phenotypes Gene Literature (17) GO Terms (5) Nucleotides (55) Proteins (33) Interactants (184) Wiki
XB-GENEPAGE-1221136

invs     inversin

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of pronephric kidney (2 sources), abnormal pronephric tubule morphology (2 sources), abnormal development of distal tubule (1 source), abnormal development of proximal tubule (1 source), abnormal pronephric kidney morphology (1 source), decreased size of the distal tubule (1 source), decreased size of the pronephric kidney (1 source), edema in embryo (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: invs assayed (6 sources)
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
nephronophthisis 2 (9AP sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + invs MO (9 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (37 sources): Abnormality of bone mineral density, Abnormality of retinal pigmentation, Absence of renal corticomedullary differentiation, Aortic valve stenosis, Ataxia, Cataract, Cholestasis, Chronic kidney disease, Chronic tubulointerstitial nephritis, Cone-shaped epiphysis, [+]
Mouse (40 sources): abdominal situs ambiguus, abnormal atrioventricular cushion morphology, abnormal direction of embryo turning, abnormal direction of heart looping, abnormal embryonic cilium location or orientation, abnormal kidney interstitium morphology, abnormal kidney morphology, abnormal kidney pelvis morphology, abnormal loop of Henle ascending limb thick segment morphology, abnormal loop of Henle descending limb morphology, [+]

View all ortholog results at Monarch