Renal insufficiency, Renal tubular atrophy, Stage 5 chronic kidney disease, Tubulointerstitial nephritis

abnormal renal tubule morphology, abnormal urine organic anion level, abnormal urine osmolality, abnormal urine urea nitrogen level, crystalluria, decreased basal metabolism, decreased bone mineral content, decreased circulating ferritin level, decreased circulating glucose level, decreased circulating iron level, decreased circulating transferrin level, decreased hematocrit, decreased hemoglobin content, decreased kidney weight, decreased percent body fat/body weight, decreased renal glomerular filtration rate, decreased susceptibility to hypertension, decreased systemic arterial systolic blood pressure, decreased urine creatinine level, decreased urine flow rate, decreased urine osmolality, decreased urine pH, decreased urine protein level, decreased urine sodium level, dilated kidney collecting duct, dilated renal glomerular capsule, dilated renal tubules, homeostasis/metabolism phenotype, increased alkaline phosphatase activity, increased blood osmolality, increased circulating alkaline phosphatase level, increased circulating antidiuretic hormone level, increased circulating creatinine level, increased creatinine clearance, increased endoplasmic reticulum stress, increased fluid intake, increased food intake, increased kidney apoptosis, increased kidney cell proliferation, increased lean body mass, increased renal glomerular filtration rate, increased urine ammonia level, increased urine creatinine level, increased urine flow rate, increased urine sodium level, no abnormal phenotype detected, renal cast, renal glomerulus cyst, renal/urinary system phenotype, urolithiasis