wnt3 Phenotypes

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Phenotypes

Gene Literature (21)

Nucleotides (55)

Interactants (190)

XB-GENEPAGE-479566

Gene Symbol: wnt3 Gene Name: Wnt family member 3

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal dorsal-ventral axis (2 sources), obsolete duplicated anatomical axis (2 sources), obsolete duplicated anterior-posterior axis (2 sources)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: wnt3 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + Hvu.wnt3 (1 source), Xla Wt + Hvu.wnt3 (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (28 sources): Abnormal lung lobation, Abnormal rib morphology, Abnormality of the larynx, Abnormally ossified vertebrae, Agenesis of corpus callosum, Anal atresia, Aplasia/Hypoplasia involving the nose, Aplasia/Hypoplasia involving the pelvis, Aplasia/Hypoplasia of the lungs, Aplasia/Hypoplasia of the nipples, Cataract, Cryptorchidism, Hydrocephalus, Iris coloboma, Microcornea, Micrognathia, Microphthalmia, Microtia, Missing ribs, Multicystic kidney dysplasia, Narrow mouth, Optic atrophy, Orofacial cleft, Polyhydramnios, Septo-optic dysplasia, Tetraamelia, Tracheal stenosis, Vaginal atresia [+]
Mouse (28 sources): abnormal apical ectodermal ridge morphology, abnormal ectoderm development, abnormal embryo size, abnormal embryonic epiblast morphology, abnormal extraembryonic endoderm formation, abnormal extraembryonic tissue morphology, abnormal forelimb morphology, abnormal germ layer development, abnormal hindlimb morphology, abnormal rostral-caudal axis patterning, absent allantois, absent amnion, absent amniotic folds, absent chorion, absent hindlimb, absent limbs, absent mesoderm, absent primitive node, absent visceral yolk sac, disorganized embryonic tissue, embryonic lethality during organogenesis, embryonic lethality during organogenesis, complete penetrance, failure of primitive streak formation, failure to gastrulate, increased ectoderm apoptosis, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, thin apical ectodermal ridge [+]
View all ortholog results at Monarch