hopx Phenotypes

Phenotypes

XB-GENEPAGE-480600

Gene Symbol: hopx Gene Name: HOP homeobox

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hopx assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (33 sources): abnormal fetal cardiomyocyte proliferation, abnormal frontal plane axis, abnormal lung development, abnormal lung-associated mesenchyme development, abnormal myocardium layer morphology, abnormal systemic arterial blood pressure, abnormal type II pneumocyte morphology, cardiac fibrosis, cardiac hypertrophy, decreased cardiac muscle contractility, decreased tidal volume, digestive/alimentary phenotype, embryonic growth arrest, embryonic lethality during organogenesis, incomplete penetrance, enlarged myocardial fiber, heart hyperplasia, impaired lung alveolus development, increased heart weight, increased left ventricle diastolic pressure, increased myocardial fiber number, increased surfactant secretion, intraventricular block, lung hemorrhage, neonatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, premature death, prolonged HV interval, prolonged P wave, prolonged QRS complex duration, thick lung-associated mesenchyme, thick ventricular wall, thin myocardium, thin myocardium compact layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (33 sources): abnormal fetal cardiomyocyte proliferation, abnormal frontal plane axis, abnormal lung development, abnormal lung-associated mesenchyme development, abnormal myocardium layer morphology, abnormal systemic arterial blood pressure, abnormal type II pneumocyte morphology, cardiac fibrosis, cardiac hypertrophy, decreased cardiac muscle contractility, [+]