igf2r Phenotypes

Summary

Expression

Phenotypes

Gene Literature (1)

XB-GENEPAGE-480956

Gene Symbol: igf2r Gene Name: insulin like growth factor 2 receptor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: igf2r assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (60 sources): abnormal body water content, abnormal craniofacial morphology, abnormal embryonic growth/weight/body size, abnormal external female genitalia morphology, abnormal lung development, abnormal motor capabilities/coordination/movement, abnormal myocardium layer morphology, abnormal uterine horn morphology, abnormal uterus morphology, absent endometrial glands, absent suckling reflex, decreased fetal weight, decreased litter size, decreased survivor rate, dilated heart, dilated heart left ventricle, dilated uterine horn, disorganized myocardium, enlarged lung, enlarged uterine horn, genetic imprinting, growth/size/body region phenotype, heart hemorrhage, heart hyperplasia, homeostasis/metabolism phenotype, impaired branching involved in preterminal bronchiole morphogenesis, increased birth body size, increased birth weight, increased body size, increased brain size, increased embryo size, increased fetal size, increased fetal weight, increased heart right ventricle size, increased heart ventricle size, increased heart weight, increased nucleated erythrocyte cell number, increased placenta weight, kinked tail, lethality throughout fetal growth and development, incomplete penetrance, liver/biliary system phenotype, liver hyperplasia, maternal imprinting, neonatal lethality, complete penetrance, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature bone ossification, prenatal lethality, complete penetrance, preweaning lethality, incomplete penetrance, pulmonary hyperplasia, reduced female fertility, reduced male fertility, reproductive system phenotype, short tail, thick interventricular septum, thick ventricular wall, thin endometrium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (60 sources): abnormal body water content, abnormal craniofacial morphology, abnormal embryonic growth/weight/body size, abnormal external female genitalia morphology, abnormal lung development, abnormal motor capabilities/coordination/movement, abnormal myocardium layer morphology, abnormal uterine horn morphology, abnormal uterus morphology, absent endometrial glands, [+]