map2k4 Phenotypes

Phenotypes

XB-GENEPAGE-482150

Gene Symbol: map2k4 Gene Name: mitogen-activated protein kinase kinase 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: map2k4 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal Purkinje cell morphology, abnormal cerebellar Purkinje cell layer, abnormal cerebellar granule layer morphology, abnormal liver bud morphology, abnormal liver development, abnormal neuron differentiation, decreased anterior commissure size, decreased corpus callosum size, decreased hepatocyte number, dilated liver sinusoidal spaces, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, impaired righting response, increased hepatocyte apoptosis, liver hemorrhage, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, complete penetrance, prenatal lethality, complete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal Purkinje cell morphology, abnormal cerebellar Purkinje cell layer, abnormal cerebellar granule layer morphology, abnormal liver bud morphology, abnormal liver development, abnormal neuron differentiation, decreased anterior commissure size, decreased corpus callosum size, decreased hepatocyte number, dilated liver sinusoidal spaces, [+]