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XB-GENEPAGE-482585
igf2 insulin like growth factor 2
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal protein phosphorylation (2 sources), decreased size of the proximal tubule (2 sources), decreased cell population proliferation in proximal tubule (1 source), decreased ribosomal protein S6 kinase activity (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Computed annotations: igf2 assayed (16 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + igf2 MO + ins MO (6 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (13 sources): Abnormal cardiovascular system morphology, Abnormality of the dentition, Asymmetry of the thorax, Cryptorchidism, Embryonal neoplasm, Facial asymmetry, Hemihypertrophy, Impaired pain sensation, Intellectual disability, mild, Myelomeningocele, [+] |
| Mouse (47 sources): abnormal bone marrow cavity morphology, abnormal cartilage development, abnormal compact bone lamellar structure, abnormal fetal cardiomyocyte proliferation, abnormal imprinting, abnormal lumbar vertebrae morphology, abnormal osteoblast differentiation, abnormal osteoclast differentiation, abnormal pancreatic beta cell physiology, abnormal placental transport, [+] |
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View all ortholog results at Monarch |