| Monarch Ortholog Phenotypes
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Human (45 sources):
Abnormal hip bone morphology,
Abnormality of the ear,
Absent phalangeal crease,
Adducted thumb,
Aplasia/Hypoplasia of the radius,
Arthrogryposis multiplex congenita,
Bilateral single transverse palmar creases,
Brachydactyly,
Broad hallux,
Calcaneovalgus deformity,
Camptodactyly,
Camptodactyly of finger,
Clinodactyly,
Distal arthrogryposis,
Downslanted palpebral fissures,
High palate,
Hip dislocation,
Joint stiffness,
Long philtrum,
Mandibular prognathia,
Metatarsus adductus,
Micrognathia,
Narrow face,
Narrow mouth,
Overlapping fingers,
Prominent nasolabial fold,
Protruding ear,
Rocker bottom foot,
Round ear,
Sandal gap,
Scoliosis,
Short neck,
Short stature,
Short toe,
Talipes equinovalgus,
Talipes equinovarus,
Tapered finger,
Tarsal synostosis,
Triangular face,
Ulnar deviation of finger,
Ulnar deviation of the hand or of fingers of the hand,
Ulnar deviation of the wrist,
Vertebral segmentation defect,
Webbed neck,
Wide nasal bridge
[+]
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Mouse (9 sources):
abnormal bone mineralization,
decreased body size,
decreased fetal size,
decreased long bone epiphyseal plate size,
kidney hemorrhage,
liver hemorrhage,
neonatal lethality, complete penetrance,
skeleton phenotype,
thin diaphragm muscle
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.