map3k12 Phenotypes

Phenotypes

XB-GENEPAGE-482767

Gene Symbol: map3k12 Gene Name: mitogen-activated protein kinase kinase kinase 12

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: map3k12 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (23 sources): abnormal anterior commissure pars anterior morphology, abnormal anterior commissure pars posterior morphology, abnormal brain internal capsule morphology, abnormal brain white matter morphology, abnormal cerebral cortex morphology, abnormal cingulum morphology, abnormal dorsal root ganglion morphology, abnormal head size, abnormal heart left ventricle size, abnormal neuron differentiation, abnormal olfactory tract morphology, absent anterior commissure, decreased cardiac output, decreased cardiac stroke volume, decreased corpus callosum size, decreased neuron apoptosis, decreased retina ganglion cell number, increased heart left ventricle size, increased motor neuron number, nervous system phenotype, postnatal lethality, complete penetrance, preweaning lethality, complete penetrance, slow Wallerian degeneration [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (23 sources): abnormal anterior commissure pars anterior morphology, abnormal anterior commissure pars posterior morphology, abnormal brain internal capsule morphology, abnormal brain white matter morphology, abnormal cerebral cortex morphology, abnormal cingulum morphology, abnormal dorsal root ganglion morphology, abnormal head size, abnormal heart left ventricle size, abnormal neuron differentiation, [+]