abnormal skeletal muscle morphology, abnormal soleus morphology, abnormal thyroxine level, arrested T cell differentiation, behavior/neurological phenotype, decreased circulating thyroxine level, decreased embryo size, decreased erythrocyte cell number, decreased gonadal fat pad weight, decreased hematocrit, decreased liver glycogen level, decreased percent body fat/body weight, decreased respiratory quotient, decreased susceptibility to diet-induced obesity, decreased susceptibility to induced hypothermia, decreased white fat cell size, endocrine/exocrine gland phenotype, enhanced exercise endurance, homeostasis/metabolism phenotype, increased basal metabolism, increased circulating ketone body level, increased energy expenditure, increased food intake, increased heart weight, increased insulin sensitivity, increased left ventricle weight, increased nucleated erythrocyte cell number, increased oxygen consumption, increased skeletal muscle fiber diameter, lethality throughout fetal growth and development, complete penetrance, shortened circadian behavior period, small liver, small thalamus, small thymus