| Monarch Ortholog Phenotypes
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Human (1 source):
Headache
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Mouse (27 sources):
abnormal electroretinogram waveform feature,
abnormal heart size,
abnormal myocardial fiber morphology,
abnormal retinal bipolar cell morphology,
abnormal retinal cone bipolar cell morphology,
abnormal retinal cone cell outer segment morphology,
abnormal retinal horizontal cell morphology,
abnormal retinal outer nuclear layer morphology,
abnormal retinal outer plexiform layer morphology,
abnormal retinal rod cell outer segment morphology,
abnormal skeletal muscle fiber type ratio,
abnormal thrombosis,
cardiac fibrosis,
decreased a-wave amplitude,
decreased b-wave amplitude,
decreased cardiac muscle contractility,
decreased retinal cone cell number,
decreased retinal rod cell number,
enlarged heart atrium,
hematopoietic system phenotype,
liver vascular congestion,
pulmonary vascular congestion,
retinal outer nuclear layer degeneration,
retinal photoreceptor degeneration,
short photoreceptor outer segment,
thin retinal outer nuclear layer,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.