Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (82) GO Terms (8) Nucleotides (78) Proteins (39) Interactants (938) Wiki
XB-GENEPAGE-485516

lef1     lymphoid enhancer binding factor 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally ventrally curved tail (2 sources), decreased size of the tail (2 sources), increased size of the head (2 sources), trunk abnormally curved dorsally (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: lef1 manipulated (5 sources)
Computed annotations: lef1 assayed (15 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + lef1 MO (7 sources), Xla Wt + lef1 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (42 sources): abnormal craniofacial morphology, abnormal embryo size, abnormal endometrial gland development, abnormal hair follicle development, abnormal hair follicle morphology, abnormal hair follicle orientation, abnormal hippocampus development, abnormal hippocampus region morphology, abnormal mammary gland bud morphology, abnormal myocardial fiber physiology, [+]