hoxa5 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-486060

Gene Symbol: hoxa5 Gene Name: homeobox A5

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hoxa5 assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (53 sources): abnormal alveolar macrophage morphology, abnormal branching involved in lung morphogenesis, abnormal bronchiole epithelium morphology, abnormal bronchiole morphology, abnormal bronchus epithelium morphology, abnormal cervical vertebrae morphology, abnormal digestive secretion, abnormal estrous cycle, abnormal larynx morphology, abnormal lung development, abnormal lung saccule morphology, abnormal lung weight, abnormal pulmonary acinus morphology, abnormal pulmonary alveolar parenchyma morphology, abnormal pulmonary alveolar sac morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary elastic fiber morphology, abnormal pulmonary interalveolar septum morphology, abnormal respiratory mucosa goblet cell morphology, abnormal surfactant secretion, abnormal thyroid gland development, abnormal tracheal cartilage morphology, abnormal xiphoid process morphology, asymmetric sternocostal joints, cervical vertebral transformation, cricoid and tracheal cartilage fusion, decreased surfactant secretion, decreased tracheal cartilage ring number, delayed ear emergence, delayed eyelid opening, impaired branching involved in bronchus morphogenesis, impaired branching involved in respiratory bronchiole morphogenesis, impaired lung alveolus development, increased circulating estradiol level, increased circulating thyroid-stimulating hormone level, increased respiratory mucosa goblet cell number, increased sternebra number, increased type II pneumocyte number, lumbar vertebral transformation, meteorism, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, overexpanded pulmonary alveoli, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, prolonged diestrus, prolonged estrous cycle, prolonged metestrus, respiratory system phenotype, short estrus, sternebra fusion, thick pulmonary interalveolar septum, trachea occlusion [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (53 sources): abnormal alveolar macrophage morphology, abnormal branching involved in lung morphogenesis, abnormal bronchiole epithelium morphology, abnormal bronchiole morphology, abnormal bronchus epithelium morphology, abnormal cervical vertebrae morphology, abnormal digestive secretion, abnormal estrous cycle, abnormal larynx morphology, abnormal lung development, [+]