prkch Phenotypes

Phenotypes

XB-GENEPAGE-486684

Gene Symbol: prkch Gene Name: protein kinase C eta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: prkch assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (23 sources): abnormal brachial lymph node morphology, abnormal cervical lymph node morphology, abnormal effector T cell morphology, abnormal grip strength, decreased CD4-positive, alpha beta T cell number, decreased DN1 thymic pro-T cell number, decreased DN4 thymocyte number, decreased T cell proliferation, decreased double-positive T cell number, decreased grip strength, delayed wound healing, enlarged axillary lymph nodes, enlarged cervical lymph nodes, enlarged inguinal lymph nodes, enlarged lymph nodes, epidermal hyperplasia, impaired wound healing, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased incidence of tumors by chemical induction, increased memory T cell number, increased skin papilloma incidence, postnatal lethality, incomplete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (23 sources): abnormal brachial lymph node morphology, abnormal cervical lymph node morphology, abnormal effector T cell morphology, abnormal grip strength, decreased CD4-positive, alpha beta T cell number, decreased DN1 thymic pro-T cell number, decreased DN4 thymocyte number, decreased T cell proliferation, decreased double-positive T cell number, decreased grip strength, [+]