hoxa2 Phenotypes

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Phenotypes

Gene Literature (25)

Nucleotides (120)

Interactants (264)

XB-GENEPAGE-488086

Gene Symbol: hoxa2 Gene Name: homeobox A2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: hoxa2 assayed (1 source)
Computed annotations: hoxa2 assayed (12 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (10 sources): Abnormal pinna morphology, Anotia, Atresia of the external auditory canal, Attention deficit hyperactivity disorder, Cleft palate, Delayed speech and language development, Holoprosencephaly, Hypoplastic helices, Microtia, Mixed hearing impairment
Mouse (75 sources): abnormal Meckel's cartilage morphology, abnormal basioccipital bone morphology, abnormal basisphenoid bone morphology, abnormal brain development, abnormal cartilage development, abnormal circulating alkaline phosphatase level, abnormal cochlear VIII nucleus morphology, abnormal craniofacial bone morphology, abnormal craniofacial morphology, abnormal cranium morphology, abnormal ear morphology, abnormal external auditory canal morphology, abnormal facial motor nucleus morphology, abnormal food intake, abnormal gonial bone morphology, abnormal hyoid bone lesser horn morphology, abnormal incudostapedial joint morphology, abnormal incus morphology, abnormal malleus morphology, abnormal middle ear ossicle morphology, abnormal neuron differentiation, abnormal otic capsule morphology, abnormal outer ear morphology, abnormal prepulse inhibition, abnormal respiratory quotient, abnormal retrotympanic process morphology, abnormal rhombomere 2 morphology, abnormal rhombomere 3 morphology, abnormal rhombomere boundary morphology, abnormal rhombomere morphology, abnormal scala vestibuli morphology, abnormal skeleton development, abnormal snout morphology, abnormal stapedial artery morphology, abnormal styloglossus muscle morphology, abnormal styloid process morphology, abnormal suckling behavior, abnormal temporal bone morphology, abnormal temporal bone squamous part morphology, abnormal temporal bone tympanic part morphology, abnormal tensor tympani muscle morphology, abnormal tongue muscle morphology, abnormal tubotympanic recess morphology, abnormal tympanic cavity morphology, abnormal tympanic membrane morphology, abnormal tympanic ring morphology, abnormal vagus nerve morphology, absent hyoid bone lesser horns, absent malleus processus brevis, absent stapedial artery, absent stapedius muscle, absent stylohyoid muscle, absent styloid process, aphagia, decreased cardiac output, decreased cardiac stroke volume, decreased food intake, decreased oligodendrocyte progenitor number, decreased prepulse inhibition, decreased respiratory quotient, decreased rhombomere 3 size, decreased sensory neuron number, enlarged gonial bone, hearing/vestibular/ear phenotype, increased oligodendrocyte progenitor number, increased rhombomere 1 size, lethality at weaning, complete penetrance, lethality throughout fetal growth and development, meteorism, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, perinatal lethality, complete penetrance, preweaning lethality, complete penetrance, small malleus processus brevis [+]
View all ortholog results at Monarch