Monarch Ortholog Phenotypes
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Mouse (44 sources):
abnormal blood cell morphology/development,
abnormal bone marrow cell physiology,
abnormal CD4-positive T cell differentiation,
abnormal definitive hematopoiesis,
abnormal embryonic erythropoiesis,
abnormal erythropoiesis,
abnormal food intake,
abnormal granulocyte differentiation,
abnormal hematopoietic stem cell morphology,
abnormal macrophage physiology,
abnormal myelopoiesis,
abnormal placenta development,
abnormal placenta labyrinth morphology,
abnormal placental labyrinth vasculature morphology,
abnormal placenta morphology,
abnormal placenta vasculature,
absent spongiotrophoblast,
decreased body fat mass,
decreased circulating free fatty acids level,
decreased embryo size,
decreased interleukin-2 secretion,
decreased spongiotrophoblast cell number,
decreased spongiotrophoblast size,
decreased susceptibility to diet-induced obesity,
decreased susceptibility to endotoxin shock,
decreased susceptibility to experimental autoimmune encephalomyelitis,
decreased T cell proliferation,
decreased thymocyte number,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality during organogenesis, incomplete penetrance,
hematopoietic system phenotype,
improved glucose tolerance,
increased erythrocyte cell number,
increased insulin sensitivity,
increased interleukin-2 secretion,
increased neutrophil cell number,
increased nucleated erythrocyte cell number,
increased susceptibility to induced arthritis,
increased trophoblast giant cell number,
lethality throughout fetal growth and development, incomplete penetrance,
liver hypoplasia,
no abnormal phenotype detected,
prenatal lethality,
small liver
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