smg1 Phenotypes

Phenotypes

XB-GENEPAGE-489704

Gene Symbol: smg1 Gene Name: SMG1 phosphatidylinositol 3-kinase-related kinase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: smg1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (35 sources): abnormal basicranium angle, abnormal cardiovascular development, abnormal circulating bilirubin level, abnormal circulating glycerol level, abnormal eye development, abnormal heart development, abnormal kidney morphology, abnormal tooth development, abnormal trophoblast layer morphology, absent optic pit, cellular phenotype, chronic inflammation, decreased cell proliferation, decreased circulating interleukin-1 beta level, decreased embryo size, delayed brain development, delayed embryo turning, embryonic growth arrest, embryonic lethality between implantation and placentation, complete penetrance, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, failure of heart looping, hematopoietic system phenotype, homeostasis/metabolism phenotype, increased B cell derived lymphoma incidence, increased body length, increased body size, increased circulating interleukin-6 level, increased embryonic tissue cell apoptosis, increased lymphoma incidence, increased tumor incidence, lethality throughout fetal growth and development, complete penetrance, premature death, preweaning lethality, complete penetrance, skeleton phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (35 sources): abnormal basicranium angle, abnormal cardiovascular development, abnormal circulating bilirubin level, abnormal circulating glycerol level, abnormal eye development, abnormal heart development, abnormal kidney morphology, abnormal tooth development, abnormal trophoblast layer morphology, absent optic pit, [+]