znf423 Phenotypes

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Phenotypes

Gene Literature (14)

Nucleotides (79)

Interactants (268)

XB-GENEPAGE-490168

Gene Symbol: znf423 Gene Name: zinc finger protein 423

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: znf423 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (70 sources): Abnormality of cardiovascular system morphology, Abnormality of neuronal migration, Abnormality of the hypothalamus-pituitary axis, Aganglionic megacolon, Agenesis of cerebellar vermis, Anteverted nares, Aortic valve stenosis, Aplasia/Hypoplasia of the cerebellar vermis, Aplasia/Hypoplasia of the corpus callosum, Apnea, Ataxia, Autistic behavior, Behavioral abnormality, Biparietal narrowing, Blindness, Brainstem dysplasia, Cerebellar vermis hypoplasia, Cholestasis, Chorioretinal coloboma, Dilated fourth ventricle, Dyspnea, Encephalocele, Enlarged kidney, Foot polydactyly, Generalized hypotonia, Global developmental delay, Gray matter heterotopia, Hand polydactyly, Hepatic fibrosis, Hepatic steatosis, Hepatomegaly, Highly arched eyebrow, Hydrocephalus, Hypertrophic cardiomyopathy, Hypoplasia of the brainstem, Intellectual disability, Intellectual disability, progressive, Intellectual disability, severe, Iris coloboma, Long face, Low-set, posteriorly rotated ears, Molar tooth sign on MRI, Muscular hypotonia, Nephronophthisis, Nephropathy, Nystagmus, Occipital meningocele, Patent ductus arteriosus, Polycystic kidney dysplasia, Postaxial foot polydactyly, Postaxial hand polydactyly, Prominent nasal bridge, Psychomotor retardation, Ptosis, Pulmonic stenosis, Renal corticomedullary cysts, Renal insufficiency, Renal tubular atrophy, Retinal degeneration, Retinal dystrophy, Scoliosis, Seizure, Situs inversus totalis, Stage 5 chronic kidney disease, Strabismus, Tachypnea, Tubulointerstitial fibrosis, Undetectable electroretinogram, Visual impairment, Wide mouth [+]
Mouse (39 sources): abnormal Purkinje cell dendrite morphology, abnormal cerebellar cortex morphology, abnormal cerebellar granule cell precursor proliferation, abnormal cerebellar plate morphology, abnormal cerebellum development, abnormal cerebellum lateral hemisphere morphology, abnormal cerebellum vermis morphology, abnormal choroid plexus morphology, abnormal embryo turning, abnormal food intake, abnormal hippocampal commissure morphology, abnormal interventricular foramen morphology, abnormal medulla oblongata morphology, abnormal nasal cavity morphology, abnormal olfactory epithelium morphology, abnormal olfactory nerve morphology, abnormal pericardium morphology, abnormal telencephalon morphology, absent cerebellum, behavior/neurological phenotype, decreased Purkinje cell number, decreased body size, decreased brain size, decreased hindbrain size, ectopic Purkinje cell, enlarged fourth ventricle, enlarged lateral ventricles, lethality at weaning, complete penetrance, lethality at weaning, incomplete penetrance, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, complete penetrance, reduced cerebellar foliation, small cerebellum, small olfactory bulb, small thalamus [+]
View all ortholog results at Monarch