pglyrp1 Phenotypes

Phenotypes

XB-GENEPAGE-491318

Gene Symbol: pglyrp1 Gene Name: peptidoglycan recognition protein 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pglyrp1 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (12 sources): abnormal crypts of Lieberkuhn morphology, abnormal gut flora balance, abnormal intestinal epithelium morphology, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, impaired granulocyte bactericidal activity, increased interleukin-6 secretion, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to induced arthritis, increased susceptibility to induced colitis, intestinal ulcer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (12 sources): abnormal crypts of Lieberkuhn morphology, abnormal gut flora balance, abnormal intestinal epithelium morphology, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, impaired granulocyte bactericidal activity, increased interleukin-6 secretion, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to induced arthritis, [+]