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Summary Expression Phenotypes Gene Literature (1) GO Terms (3) Nucleotides (113) Proteins (68) Interactants (26) Wiki
XB-GENEPAGE-491809

malt1     MALT1 paracaspase

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: malt1 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (6 sources): Delayed skeletal maturation, Growth delay, Immunodeficiency, Osteoporosis, Recurrent bacterial infections, Recurrent viral infections
Mouse (9 sources): abnormal T cell differentiation, abnormal T cell proliferation, abnormal dendritic cell physiology, abnormal double-negative T cell morphology, abnormal spleen marginal zone morphology, absent B-1a cells, decreased T cell proliferation, decreased interleukin-2 secretion, impaired humoral immune response

View all ortholog results at Monarch