ttbk2 Phenotypes

Phenotypes

XB-GENEPAGE-493334

Gene Symbol: ttbk2 Gene Name: tau tubulin kinase 2

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (14 sources): Abnormal pyramidal sign, Cerebellar atrophy, Dysarthria, Dysphagia, Dystonia, Gait imbalance, Horizontal nystagmus, Hyperreflexia, Jerky ocular pursuit movements, Nystagmus, obsolete Difficulty walking, Peripheral neuropathy, Progressive cerebellar ataxia, Vertical nystagmus [+]
Mouse (21 sources): abnormal brain development, abnormal cell morphology, abnormal cranial flexure morphology, abnormal direction of heart looping, abnormal embryonic tissue morphology, abnormal embryo size, abnormal embryo turning, abnormal limb development, abnormal nervous system development, abnormal pericardium morphology, abnormal somite shape, abnormal tail bud morphology, absent embryonic cilia, decreased embryo size, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, incomplete embryo turning, nervous system phenotype, perinatal lethality, complete penetrance, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance [+]
View all ortholog results at Monarch