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Summary Expression Phenotypes Gene Literature (67) GO Terms (12) Nucleotides (108) Proteins (41) Interactants (885) Wiki
XB-GENEPAGE-494124

foxi1     forkhead box I1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally localised ectodermal cell (2 sources), abnormal axis elongation (1 source), abnormal cell adhesion (1 source), abnormal ciliated epidermal cell (1 source), abnormal development of cement gland (1 source), abnormal development of ectodermal cell (1 source), abnormal development of neural tube (1 source), abnormal ectoderm morphology (1 source), abnormal mesoderm morphology (1 source), abnormally decreased number of cilium in the ciliated epidermal cell (1 source), abnormally incomplete structure of epidermis (1 source), abnormally increased number of ciliated cell (1 source), abnormally increased number of non-ciliated epithelial cell (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: foxi1 manipulated (10 sources), foxi1 assayed (8 sources)
Computed annotations: foxi1 manipulated (3 sources), foxi1 assayed (41 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + CAnotch1 + foxi1 - animal cap explant (3 sources), Xla Wt + foxi1 (2 sources), Xla Wt + foxi1 MO (2 sources), Xla Wt + foxi1 MO + animal cap explant (2 sources), Xla Wt + foxi1 MO + animal cap explant (2 sources), Xla Wt + dnbmp7.1 + foxi1 MO + animal cap explant (2 sources), Xla Wt + foxi1 (1 source), Xla Wt + foxi1 (1 source), Xla Wt + foxi1 (1 source), Xla Wt + foxi1 + foxi1 MO (1 source), Xla Wt + foxi1 + vegetal hemisphere explant (1 source), Xla Wt + foxi1 MO (1 source), Xla Wt + foxi1 MO (1 source), Xla Wt + foxi1 MO + Activin + animal cap explant (1 source), Xla Wt + foxi1-GR + DEX (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (21 sources): Abnormality of metabolism/homeostasis, Abnormality of the inner ear, Ataxia, Cochlear malformation, Compensated hypothyroidism, Congenital sensorineural hearing impairment, Enlarged vestibular aqueduct, Goiter, Hyperparathyroidism, Hypoplasia of the cochlea, [+]
Mouse (34 sources): abnormal cochlea morphology, abnormal common crus morphology, abnormal epididymis morphology, abnormal kidney collecting duct epithelium morphology, abnormal membranous labyrinth morphology, abnormal sperm physiology, abnormal temporal bone morphology, absent cochlear modiolus, absent endocochlear potential, absent otoliths, [+]

View all ortholog results at Monarch